Treatment and recovery of Wagner 5 diabetic foot with Heberprot-P

To improve the quality of life of diabetic patients suffering from diabetic foot ulcers, and trying to diminish or avoid major amputations among them, we tested the use of Heberprot-P® (epidermal growth factor) in seventy of those patients having Wagner’s grade 5 diabetic foot. The product was admin...

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Main Authors: José Fernández Montequin, Gabriela Mena, Llipsy Santiesteban
Format: Article
Language:English
Published: Elfos Scientiae
Series:Biotecnología Aplicada
Subjects:
Online Access:http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1027-28522010000200005&lng=en&tlng=en
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author José Fernández Montequin
Gabriela Mena
Llipsy Santiesteban
author_facet José Fernández Montequin
Gabriela Mena
Llipsy Santiesteban
author_sort José Fernández Montequin
collection DOAJ
description To improve the quality of life of diabetic patients suffering from diabetic foot ulcers, and trying to diminish or avoid major amputations among them, we tested the use of Heberprot-P® (epidermal growth factor) in seventy of those patients having Wagner’s grade 5 diabetic foot. The product was administered by intralesional injection, three times a week. Twelve patients (17.1%) were amputated and seven (9%) abandoned the treatment. Otherwise, twenty eight patients (40%) saved their legs, and 23(32.8%) are currently being administered with 75 µg of Heberprot-P (EGF), with good results. Until this moment, Heberprot-P constitutes an answer for diabetic patients having diabetic foot grade 5 in the Wagner scale.
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spelling doaj.art-382153490ce74fcc9b654db939c5194f2022-12-22T02:05:10ZengElfos ScientiaeBiotecnología Aplicada1027-2852272113115S1027-28522010000200005Treatment and recovery of Wagner 5 diabetic foot with Heberprot-PJosé Fernández Montequin0Gabriela Mena1Llipsy Santiesteban2Instituto de Angiología y Cirugía VascularHospital Militar Carlos ArveloHospital Clínico Quirúrgico Hermanos AmeijeirasTo improve the quality of life of diabetic patients suffering from diabetic foot ulcers, and trying to diminish or avoid major amputations among them, we tested the use of Heberprot-P® (epidermal growth factor) in seventy of those patients having Wagner’s grade 5 diabetic foot. The product was administered by intralesional injection, three times a week. Twelve patients (17.1%) were amputated and seven (9%) abandoned the treatment. Otherwise, twenty eight patients (40%) saved their legs, and 23(32.8%) are currently being administered with 75 µg of Heberprot-P (EGF), with good results. Until this moment, Heberprot-P constitutes an answer for diabetic patients having diabetic foot grade 5 in the Wagner scale.http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1027-28522010000200005&lng=en&tlng=enischemic diabetic foothuman recombinant epidermal growth factordiabetic foot wagner 5wagner classification
spellingShingle José Fernández Montequin
Gabriela Mena
Llipsy Santiesteban
Treatment and recovery of Wagner 5 diabetic foot with Heberprot-P
Biotecnología Aplicada
ischemic diabetic foot
human recombinant epidermal growth factor
diabetic foot wagner 5
wagner classification
title Treatment and recovery of Wagner 5 diabetic foot with Heberprot-P
title_full Treatment and recovery of Wagner 5 diabetic foot with Heberprot-P
title_fullStr Treatment and recovery of Wagner 5 diabetic foot with Heberprot-P
title_full_unstemmed Treatment and recovery of Wagner 5 diabetic foot with Heberprot-P
title_short Treatment and recovery of Wagner 5 diabetic foot with Heberprot-P
title_sort treatment and recovery of wagner 5 diabetic foot with heberprot p
topic ischemic diabetic foot
human recombinant epidermal growth factor
diabetic foot wagner 5
wagner classification
url http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1027-28522010000200005&lng=en&tlng=en
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