Treatment and recovery of Wagner 5 diabetic foot with Heberprot-P
To improve the quality of life of diabetic patients suffering from diabetic foot ulcers, and trying to diminish or avoid major amputations among them, we tested the use of Heberprot-P® (epidermal growth factor) in seventy of those patients having Wagner’s grade 5 diabetic foot. The product was admin...
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Format: | Article |
Language: | English |
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Elfos Scientiae
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Series: | Biotecnología Aplicada |
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Online Access: | http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1027-28522010000200005&lng=en&tlng=en |
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author | José Fernández Montequin Gabriela Mena Llipsy Santiesteban |
author_facet | José Fernández Montequin Gabriela Mena Llipsy Santiesteban |
author_sort | José Fernández Montequin |
collection | DOAJ |
description | To improve the quality of life of diabetic patients suffering from diabetic foot ulcers, and trying to diminish or avoid major amputations among them, we tested the use of Heberprot-P® (epidermal growth factor) in seventy of those patients having Wagner’s grade 5 diabetic foot. The product was administered by intralesional injection, three times a week. Twelve patients (17.1%) were amputated and seven (9%) abandoned the treatment. Otherwise, twenty eight patients (40%) saved their legs, and 23(32.8%) are currently being administered with 75 µg of Heberprot-P (EGF), with good results. Until this moment, Heberprot-P constitutes an answer for diabetic patients having diabetic foot grade 5 in the Wagner scale. |
first_indexed | 2024-04-14T07:51:36Z |
format | Article |
id | doaj.art-382153490ce74fcc9b654db939c5194f |
institution | Directory Open Access Journal |
issn | 1027-2852 |
language | English |
last_indexed | 2024-04-14T07:51:36Z |
publisher | Elfos Scientiae |
record_format | Article |
series | Biotecnología Aplicada |
spelling | doaj.art-382153490ce74fcc9b654db939c5194f2022-12-22T02:05:10ZengElfos ScientiaeBiotecnología Aplicada1027-2852272113115S1027-28522010000200005Treatment and recovery of Wagner 5 diabetic foot with Heberprot-PJosé Fernández Montequin0Gabriela Mena1Llipsy Santiesteban2Instituto de Angiología y Cirugía VascularHospital Militar Carlos ArveloHospital Clínico Quirúrgico Hermanos AmeijeirasTo improve the quality of life of diabetic patients suffering from diabetic foot ulcers, and trying to diminish or avoid major amputations among them, we tested the use of Heberprot-P® (epidermal growth factor) in seventy of those patients having Wagner’s grade 5 diabetic foot. The product was administered by intralesional injection, three times a week. Twelve patients (17.1%) were amputated and seven (9%) abandoned the treatment. Otherwise, twenty eight patients (40%) saved their legs, and 23(32.8%) are currently being administered with 75 µg of Heberprot-P (EGF), with good results. Until this moment, Heberprot-P constitutes an answer for diabetic patients having diabetic foot grade 5 in the Wagner scale.http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1027-28522010000200005&lng=en&tlng=enischemic diabetic foothuman recombinant epidermal growth factordiabetic foot wagner 5wagner classification |
spellingShingle | José Fernández Montequin Gabriela Mena Llipsy Santiesteban Treatment and recovery of Wagner 5 diabetic foot with Heberprot-P Biotecnología Aplicada ischemic diabetic foot human recombinant epidermal growth factor diabetic foot wagner 5 wagner classification |
title | Treatment and recovery of Wagner 5 diabetic foot with Heberprot-P |
title_full | Treatment and recovery of Wagner 5 diabetic foot with Heberprot-P |
title_fullStr | Treatment and recovery of Wagner 5 diabetic foot with Heberprot-P |
title_full_unstemmed | Treatment and recovery of Wagner 5 diabetic foot with Heberprot-P |
title_short | Treatment and recovery of Wagner 5 diabetic foot with Heberprot-P |
title_sort | treatment and recovery of wagner 5 diabetic foot with heberprot p |
topic | ischemic diabetic foot human recombinant epidermal growth factor diabetic foot wagner 5 wagner classification |
url | http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1027-28522010000200005&lng=en&tlng=en |
work_keys_str_mv | AT josefernandezmontequin treatmentandrecoveryofwagner5diabeticfootwithheberprotp AT gabrielamena treatmentandrecoveryofwagner5diabeticfootwithheberprotp AT llipsysantiesteban treatmentandrecoveryofwagner5diabeticfootwithheberprotp |