KLK11 promotes the activation of mTOR and protein synthesis to facilitate cardiac hypertrophy

KLK11 promotes the activation of mTOR and protein synthesis to facilitate cardiac hypertrophy

Abstract Background Cardiovascular diseases have become the leading cause of death worldwide, and cardiac hypertrophy is the core mechanism underlying cardiac defect and heart failure. However, the underlying mechanisms of cardiac hypertrophy are not fully understood. Here we investigated the roles...

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Bibliographic Details
Main Authors: Yi Wang, Hongjuan Liao, Yueheng Wang, Jinlin Zhou, Feng Wang, Yingxin Xie, Kun Zhao, Weinian Gao
Format: Article
Language:English
Published: BMC 2021-05-01
Series:BMC Cardiovascular Disorders
Subjects:
KLK11
Cardiac hypertrophy
Protein synthesis
MTOR
Akt
Online Access:https://doi.org/10.1186/s12872-021-02053-y

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