Analysis of gene expression EGFR and KRAS, microRNA-21 and microRNA-203 in patients with colon and rectal cancer and correlation with clinical outcome and prognostic factors

Analysis of gene expression EGFR and KRAS, microRNA-21 and microRNA-203 in patients with colon and rectal cancer and correlation with clinical outcome and prognostic factors

Abstract Purpose: To evaluate the expression of EGFR, KRAS genes, microRNAs-21 and 203 in colon and rectal cancer samples, correlated with their age at diagnosis, histological subtype, value of pretreatment CEA, TNM staging and clinical outcome. Methods: Expression of genes and microRNAs by real...

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Bibliographic Details
Main Authors: Thais Inácio de Carvalho, Paulo Cezar Novais, Fermino Sanches Lizarte Neto, Renata Danielle Sicchieri, Marcella Suelma Torrecillas Rosa, Camila Albuquerque Mello de Carvalho, Daniela Pretti da Cunha Tirapelli, Fernanda Maris Peria, José Joaquim Ribeiro da Rocha, Omar Féres
Format: Article
Language:English
Published: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2017-03-01
Series:Acta Cirúrgica Brasileira
Subjects:
Colonic Neoplasms. Rectal Neoplasms. Genes
erbB-1. MicroRNAs.
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502017000300243&tlng=en

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