Investigating dysautonomia of Bradbury Eggleston syndrome: A case report

This is a report of 65 years old man with recurrent episodes of dizziness while standing from supine position and history of constipation and nocturia since last 6 months. Patient disclosed no significant past history other than treated pulmonary tuberculosis 5 years back. The general mental state a...

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Bibliographic Details
Main Authors: Soumayata Somendra, Amit Tak, Jyotsna Shukla, Kapil Gupta, Jitendra Gupta
Format: Article
Language:English
Published: Amaltea Medical Publishing House 2021-09-01
Series:Romanian Journal of Neurology
Subjects:
Online Access:https://rjn.com.ro/articles/2021.3/RJN_2021_3_Art-20.pdf
Description
Summary:This is a report of 65 years old man with recurrent episodes of dizziness while standing from supine position and history of constipation and nocturia since last 6 months. Patient disclosed no significant past history other than treated pulmonary tuberculosis 5 years back. The general mental state and vital parameters were within normal limits. Autonomic function tests and heart rate variability analysis measured autonomic reactivity and tone respectively. The tests revealed that autonomic dysfunction include severe sympathetic and mild parasympathetic involvement. After exclusion of other possible causes of orthostatic hypertension, diagnosis of pure autonomic failure also known as Bradbury Eggleston syndrome was established. Treatment with fludrocortisones and non-pharmacological interventions improved orthostatic tolerance.
ISSN:1843-8148
2069-6094