Single cell analysis in head and neck cancer reveals potential immune evasion mechanisms during early metastasis
The molecular mechanisms underlying lymph-node metastasis in head and neck squamous-cell carcinoma remain to be investigated. Here, the authors perform single-cell RNA sequencing of cancer cells and CD8 + T cells and suggest potential mechanisms of immune evasion during early metastasis.
Bibliographic Details
Main Authors: |
Hong Sheng Quah,
Elaine Yiqun Cao,
Lisda Suteja,
Constance H. Li,
Hui Sun Leong,
Fui Teen Chong,
Shilpi Gupta,
Camille Arcinas,
John F. Ouyang,
Vivian Ang,
Teja Celhar,
Yunqian Zhao,
Hui Chen Tay,
Jerry Chan,
Takeshi Takahashi,
Daniel S. W. Tan,
Subhra K. Biswas,
Owen J. L. Rackham,
N. Gopalakrishna Iyer |
Format: | Article
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Language: | English |
Published: |
Nature Portfolio
2023-03-01
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Series: | Nature Communications
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Online Access: | https://doi.org/10.1038/s41467-023-37379-y
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