Are physicians ready for precision antibiotic prescribing? A qualitative analysis of the acceptance of artificial intelligence-enabled clinical decision support systems in India and Singapore

ABSTRACT: Objectives: Artificial intelligence (AI)-driven clinical decision support systems (CDSSs) can augment antibiotic decision-making capabilities, but physicians’ hesitancy in adopting them may undermine their utility. We conducted a cross-country comparison of physician perceptions on the ba...

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Κύριοι συγγραφείς: Zhilian Huang, Mithun Mohan George, Yi-Roe Tan, Karthiga Natarajan, Emily Devasagayam, Evonne Tay, Abi Manesh, George M. Varghese, Ooriapadickal Cherian Abraham, Anand Zachariah, Peiling Yap, Dorothy Lall, Angela Chow
Μορφή: Άρθρο
Γλώσσα:English
Έκδοση: Elsevier 2023-12-01
Σειρά:Journal of Global Antimicrobial Resistance
Θέματα:
Διαθέσιμο Online:http://www.sciencedirect.com/science/article/pii/S2213716523001406
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author Zhilian Huang
Mithun Mohan George
Yi-Roe Tan
Karthiga Natarajan
Emily Devasagayam
Evonne Tay
Abi Manesh
George M. Varghese
Ooriapadickal Cherian Abraham
Anand Zachariah
Peiling Yap
Dorothy Lall
Angela Chow
author_facet Zhilian Huang
Mithun Mohan George
Yi-Roe Tan
Karthiga Natarajan
Emily Devasagayam
Evonne Tay
Abi Manesh
George M. Varghese
Ooriapadickal Cherian Abraham
Anand Zachariah
Peiling Yap
Dorothy Lall
Angela Chow
author_sort Zhilian Huang
collection DOAJ
description ABSTRACT: Objectives: Artificial intelligence (AI)-driven clinical decision support systems (CDSSs) can augment antibiotic decision-making capabilities, but physicians’ hesitancy in adopting them may undermine their utility. We conducted a cross-country comparison of physician perceptions on the barriers and facilitators in accepting an AI-enabled CDSS for antibiotic prescribing. Methods: We conducted in-depth interviews with physicians from the National Centre for Infectious Diseases (NCID), Singapore, and Christian Medical College Vellore (CMCV), India, between April and December 2022. Our semi-structured in-depth interview guides were anchored on Venkatesh's UTAUT model. We used clinical vignettes to illustrate the application of AI in clinical decision support for antibiotic prescribing and explore medico-legal concerns. Results: Most NCID physicians felt that an AI-enabled CDSS could facilitate antibiotic prescribing, while most CMCV physicians were sceptical about the tool's utility. The hesitancy in adopting an AI-enabled CDSS stems from concerns about the lack of validated and successful examples, fear of losing autonomy and clinical skills, difficulty of use, and impediment in work efficiency. Physicians from both sites felt that a user-friendly interface, integration with workflow, transparency of output, a guiding medico-legal framework, and training and technical support would improve the uptake of an AI-enabled CDSS. Conclusion: In conclusion, the acceptance of AI-enabled CDSSs depends on the physician's confidence with the tool's recommendations, perceived ease of use, familiarity with AI, the organisation's digital culture and support, and the presence of medico-legal governance of AI. Progressive implementation and continuous feedback are essential to allay scepticism around the utility of AI-enabled CDSSs.
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spelling doaj.art-3827b8f1a80f412cb85ba4b0799e77cf2023-11-29T04:24:23ZengElsevierJournal of Global Antimicrobial Resistance2213-71652023-12-01357685Are physicians ready for precision antibiotic prescribing? A qualitative analysis of the acceptance of artificial intelligence-enabled clinical decision support systems in India and SingaporeZhilian Huang0Mithun Mohan George1Yi-Roe Tan2Karthiga Natarajan3Emily Devasagayam4Evonne Tay5Abi Manesh6George M. Varghese7Ooriapadickal Cherian Abraham8Anand Zachariah9Peiling Yap10Dorothy Lall11Angela Chow12Infectious Diseases Research and Training Office, National Centre for Infectious Diseases, Singapore; Department of Preventive and Population Medicine, Office of Clinical Epidemiology, Analytics, and Knowledge [OCEAN], Tan Tock Seng Hospital, SingaporeDepartment of Infectious Diseases, Christian Medical College, Vellore, Tamil Nadu, IndiaInternational Digital Health & AI Research Collaborative (I-DAIR), Geneva, SwitzerlandInfectious Diseases Research and Training Office, National Centre for Infectious Diseases, Singapore; Department of Preventive and Population Medicine, Office of Clinical Epidemiology, Analytics, and Knowledge [OCEAN], Tan Tock Seng Hospital, SingaporeDepartment of Infectious Diseases, Christian Medical College, Vellore, Tamil Nadu, IndiaInfectious Diseases Research and Training Office, National Centre for Infectious Diseases, Singapore; Department of Preventive and Population Medicine, Office of Clinical Epidemiology, Analytics, and Knowledge [OCEAN], Tan Tock Seng Hospital, SingaporeDepartment of Infectious Diseases, Christian Medical College, Vellore, Tamil Nadu, IndiaDepartment of Infectious Diseases, Christian Medical College, Vellore, Tamil Nadu, IndiaDepartment of Medicine, Christian Medical College, Vellore, Tamil Nadu, IndiaDepartment of Medicine, Christian Medical College, Vellore, Tamil Nadu, IndiaInternational Digital Health & AI Research Collaborative (I-DAIR), Geneva, SwitzerlandDepartment of Community Health, Christian Medical College Vellore - Chittoor Campus, Andhra Pradesh, India; Alternative corresponding author. Mailing address: Department of Community Health, Christian Medical College Vellore - Chittoor Campus, Andhra Pradesh, India 517002.Infectious Diseases Research and Training Office, National Centre for Infectious Diseases, Singapore; Department of Preventive and Population Medicine, Office of Clinical Epidemiology, Analytics, and Knowledge [OCEAN], Tan Tock Seng Hospital, Singapore; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore; Saw Swee Hock School of Public Health, National University of Singapore, Singapore; Corresponding author. Mailing address: Department of Preventive and Population Medicine, Office of Clinical Epidemiology, Analytics, and Knowledge [OCEAN], Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore 308433.ABSTRACT: Objectives: Artificial intelligence (AI)-driven clinical decision support systems (CDSSs) can augment antibiotic decision-making capabilities, but physicians’ hesitancy in adopting them may undermine their utility. We conducted a cross-country comparison of physician perceptions on the barriers and facilitators in accepting an AI-enabled CDSS for antibiotic prescribing. Methods: We conducted in-depth interviews with physicians from the National Centre for Infectious Diseases (NCID), Singapore, and Christian Medical College Vellore (CMCV), India, between April and December 2022. Our semi-structured in-depth interview guides were anchored on Venkatesh's UTAUT model. We used clinical vignettes to illustrate the application of AI in clinical decision support for antibiotic prescribing and explore medico-legal concerns. Results: Most NCID physicians felt that an AI-enabled CDSS could facilitate antibiotic prescribing, while most CMCV physicians were sceptical about the tool's utility. The hesitancy in adopting an AI-enabled CDSS stems from concerns about the lack of validated and successful examples, fear of losing autonomy and clinical skills, difficulty of use, and impediment in work efficiency. Physicians from both sites felt that a user-friendly interface, integration with workflow, transparency of output, a guiding medico-legal framework, and training and technical support would improve the uptake of an AI-enabled CDSS. Conclusion: In conclusion, the acceptance of AI-enabled CDSSs depends on the physician's confidence with the tool's recommendations, perceived ease of use, familiarity with AI, the organisation's digital culture and support, and the presence of medico-legal governance of AI. Progressive implementation and continuous feedback are essential to allay scepticism around the utility of AI-enabled CDSSs.http://www.sciencedirect.com/science/article/pii/S2213716523001406Antimicrobial resistanceArtificial intelligenceClinical decision support systemAntibiotic prescribing
spellingShingle Zhilian Huang
Mithun Mohan George
Yi-Roe Tan
Karthiga Natarajan
Emily Devasagayam
Evonne Tay
Abi Manesh
George M. Varghese
Ooriapadickal Cherian Abraham
Anand Zachariah
Peiling Yap
Dorothy Lall
Angela Chow
Are physicians ready for precision antibiotic prescribing? A qualitative analysis of the acceptance of artificial intelligence-enabled clinical decision support systems in India and Singapore
Journal of Global Antimicrobial Resistance
Antimicrobial resistance
Artificial intelligence
Clinical decision support system
Antibiotic prescribing
title Are physicians ready for precision antibiotic prescribing? A qualitative analysis of the acceptance of artificial intelligence-enabled clinical decision support systems in India and Singapore
title_full Are physicians ready for precision antibiotic prescribing? A qualitative analysis of the acceptance of artificial intelligence-enabled clinical decision support systems in India and Singapore
title_fullStr Are physicians ready for precision antibiotic prescribing? A qualitative analysis of the acceptance of artificial intelligence-enabled clinical decision support systems in India and Singapore
title_full_unstemmed Are physicians ready for precision antibiotic prescribing? A qualitative analysis of the acceptance of artificial intelligence-enabled clinical decision support systems in India and Singapore
title_short Are physicians ready for precision antibiotic prescribing? A qualitative analysis of the acceptance of artificial intelligence-enabled clinical decision support systems in India and Singapore
title_sort are physicians ready for precision antibiotic prescribing a qualitative analysis of the acceptance of artificial intelligence enabled clinical decision support systems in india and singapore
topic Antimicrobial resistance
Artificial intelligence
Clinical decision support system
Antibiotic prescribing
url http://www.sciencedirect.com/science/article/pii/S2213716523001406
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