TRIF is a critical negative regulator of TLR agonist mediated activation of dendritic cells in vivo.

TRIF is a critical negative regulator of TLR agonist mediated activation of dendritic cells in vivo.

Despite recent advances in developing and licensing adjuvants, there is a great need for more potent formulations to enhance immunogenicity of vaccines. An Eimeria tenella derived antigen (rEA) augments immune responses against several pathogens in animal models and recently was confirmed to be safe...

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Bibliographic Details
Main Authors: Sergey S Seregin, Yasser A Aldhamen, Daniel M Appledorn, Charles F Aylsworth, Sarah Godbehere, Chyong-Jy Joyce Liu, Dionisia Quiroga, Andrea Amalfitano
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3132756?pdf=render

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