Development of a Quantitative Chromatographic Fingerprint Analysis Method for Sugar Components of Xiaochaihu Capsules Based on Quality by Design Concept

Development of a Quantitative Chromatographic Fingerprint Analysis Method for Sugar Components of Xiaochaihu Capsules Based on Quality by Design Concept

Background: Xiaochaihu capsule is composed of seven traditional Chinese medicines. The pharmacopoeia only focuses on the quantitative detection of baicalin, which cannot fully reflect the quality of the preparation. Some medium polar components were used to establish the fingerprint of Xiaochaihu ca...

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Bibliographic Details
Main Authors: Jing Lan, Gelin Wu, Linlin Wu, Haibin Qu, Ping Gong, Yongjian Xie, Peng Zhou, Xingchu Gong
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Separations
Subjects:
quality by design
Xiaochaihu capsule
quantitative chromatographic fingerprint
design space
definitive screening design
Plackett–Burman
Online Access:https://www.mdpi.com/2297-8739/10/1/13

Internet

https://www.mdpi.com/2297-8739/10/1/13

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