Immediate Insulin Treatment Prevents Diabetes-Induced Gut Region-Specific Increase in the Number of Myenteric Serotonergic Neurons

Immediate Insulin Treatment Prevents Diabetes-Induced Gut Region-Specific Increase in the Number of Myenteric Serotonergic Neurons

To evaluate the effects of hyperglycemia and insulin treatment on the proportion of serotonin-immunoreactive (5-HT-IR) myenteric neurons, samples were taken from the duodenum, ileum, and colon of diabetic, insulin-treated diabetic, and control rats 10 weeks after the onset of streptozotocin-induced...

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Bibliographic Details
Main Authors: Diána Mezei, Nikolett Bódi, Zita Szalai, Zsuzsanna Márton, János Balázs, Mária Bagyánszki
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Applied Sciences
Subjects:
diabetic enteropathy
gut segment specificity
myenteric neurons
serotonin
type 1 diabetes
enteric nervous system
Online Access:https://www.mdpi.com/2076-3417/11/13/5949

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