New Targets for Molecular Therapy of Biliary Malignant Tumors
Biliary tract cancer is a group of epithelial cancers associated with the biliary tract. They are anatomically divided into intrahepatic (iCCA), perihilar (pCCA) and distal (dCCA) subgroups. Up to now, surgical treatment is still the main treatment for malignant biliary tumors, but many patients are...
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Magazine House of Cancer Research on Prevention and Treatment
2020-01-01
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Series: | Zhongliu Fangzhi Yanjiu |
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Online Access: | http://html.rhhz.net/ZLFZYJ/html/8578.2020.19.0473.htm |
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author | LYU Hong LYU Zhicheng LIU Guangde |
author_facet | LYU Hong LYU Zhicheng LIU Guangde |
author_sort | LYU Hong |
collection | DOAJ |
description | Biliary tract cancer is a group of epithelial cancers associated with the biliary tract. They are anatomically divided into intrahepatic (iCCA), perihilar (pCCA) and distal (dCCA) subgroups. Up to now, surgical treatment is still the main treatment for malignant biliary tumors, but many patients are in advanced stage when they were diagnosed, the opportunity for surgery was lost, and there is still no effective chemotherapy program. Therefore, it is urgent to find an effective targeted drug. In this paper, we discuss some new ideas and molecular research of malignant biliary tumors in recent years. These molecules may be the promising targets for future treatment of malignant biliary tumors. |
first_indexed | 2024-12-11T23:44:27Z |
format | Article |
id | doaj.art-3830f891c2ca4a6cbb33da3a62f3341d |
institution | Directory Open Access Journal |
issn | 1000-8578 1000-8578 |
language | zho |
last_indexed | 2024-12-11T23:44:27Z |
publishDate | 2020-01-01 |
publisher | Magazine House of Cancer Research on Prevention and Treatment |
record_format | Article |
series | Zhongliu Fangzhi Yanjiu |
spelling | doaj.art-3830f891c2ca4a6cbb33da3a62f3341d2022-12-22T00:45:38ZzhoMagazine House of Cancer Research on Prevention and TreatmentZhongliu Fangzhi Yanjiu1000-85781000-85782020-01-01471778010.3971/j.issn.1000-8578.2020.19.04738578.2020.19.0473New Targets for Molecular Therapy of Biliary Malignant TumorsLYU Hong0LYU Zhicheng1LIU Guangde2Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai 200032, ChinaDepartment of General Surgery, The Seventh Hospital of Chongqing, Chongqing 400050, ChinaOutpatient Department of Former Lanzhou Military Region, Lanzhou 730000, ChinaBiliary tract cancer is a group of epithelial cancers associated with the biliary tract. They are anatomically divided into intrahepatic (iCCA), perihilar (pCCA) and distal (dCCA) subgroups. Up to now, surgical treatment is still the main treatment for malignant biliary tumors, but many patients are in advanced stage when they were diagnosed, the opportunity for surgery was lost, and there is still no effective chemotherapy program. Therefore, it is urgent to find an effective targeted drug. In this paper, we discuss some new ideas and molecular research of malignant biliary tumors in recent years. These molecules may be the promising targets for future treatment of malignant biliary tumors.http://html.rhhz.net/ZLFZYJ/html/8578.2020.19.0473.htmcholangiocarcinomamolecular targetstargeted drugs |
spellingShingle | LYU Hong LYU Zhicheng LIU Guangde New Targets for Molecular Therapy of Biliary Malignant Tumors Zhongliu Fangzhi Yanjiu cholangiocarcinoma molecular targets targeted drugs |
title | New Targets for Molecular Therapy of Biliary Malignant Tumors |
title_full | New Targets for Molecular Therapy of Biliary Malignant Tumors |
title_fullStr | New Targets for Molecular Therapy of Biliary Malignant Tumors |
title_full_unstemmed | New Targets for Molecular Therapy of Biliary Malignant Tumors |
title_short | New Targets for Molecular Therapy of Biliary Malignant Tumors |
title_sort | new targets for molecular therapy of biliary malignant tumors |
topic | cholangiocarcinoma molecular targets targeted drugs |
url | http://html.rhhz.net/ZLFZYJ/html/8578.2020.19.0473.htm |
work_keys_str_mv | AT lyuhong newtargetsformoleculartherapyofbiliarymalignanttumors AT lyuzhicheng newtargetsformoleculartherapyofbiliarymalignanttumors AT liuguangde newtargetsformoleculartherapyofbiliarymalignanttumors |