Preoperative fibrinogen is associated with the clinical survival of primary liver cancer patients and promotes hepatoma metastasis via the PTEN/AKT/mTOR pathway

Preoperative fibrinogen is associated with the clinical survival of primary liver cancer patients and promotes hepatoma metastasis via the PTEN/AKT/mTOR pathway

Aim: Hyperfibrinogenemia had been widely observed in various cancer patients, however, whether fibrinogen (FIB) influences the survival outcome of patients with primary liver cancer (PLC) remains unknown. This study was aimed to evaluate the predictive value of preoperative FIB in the survival outco...

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Bibliographic Details
Main Authors: Xuemeng Qian, Jiajing Cai, Qi Qi, Jia Han, Xinfang Zhu, Rong Xia, Qi Zhang
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Heliyon
Subjects:
Fibrinogen
Primary liver cancer
Survival
Epithelial-mesenchymal transition
PTEN/AKT/mTOR pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023039038

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