Evaluation of biases present in the cohort multiple randomised controlled trial design: a simulation study

Evaluation of biases present in the cohort multiple randomised controlled trial design: a simulation study

Abstract Background The cohort multiple randomised controlled trial (cmRCT) design provides an opportunity to incorporate the benefits of randomisation within clinical practice; thus reducing costs, integrating electronic healthcare records, and improving external validity. This study aims to addres...

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Bibliographic Details
Main Authors: Jane Candlish, Alexander Pate, Matthew Sperrin, Tjeerd van Staa, on behalf of GetReal Work Package 2
Format: Article
Language:English
Published: BMC 2017-01-01
Series:BMC Medical Research Methodology
Subjects:
Trials within cohorts
Cohort multiple randomised controlled trial
Pragmatic trial
Instrumental variable
Online Access:http://link.springer.com/article/10.1186/s12874-017-0295-7

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