EVALUATION OF THE EXPRESSION OF TRANSCRIPTION, NEOANGIOGENESIS AND APOPTOSIS FACTORS IN CASE OF POSTOPERATIVE COMPLICATIONS IN PATIENTS WITH DIFFERENT PROGRESSION OF ORAL MUCOSA CANCER

While studying the expression of transcription, neoangiogenesis and apoptosis factors in the tumour tissue and oral fluid of 141 patients with oral mucosa cancer T1-3N0-2M0, it was shown that oral mucosa cancer progression combined with postoperative purulent inflammatory complications were associat...

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Main Authors: V. I. KONONENKO, O. I. KIT, E. F. KOMAROVA, A. Yu. MAKSIMOV, V. V. POZDNYAKOVA, I. A. NOVIKOVA, A. A. DEMIDOVA
Format: Article
Language:Russian
Published: Ministry of Healthcare of the Russian Federation. “Kuban State Medical University” 2017-05-01
Series:Кубанский научный медицинский вестник
Subjects:
Online Access:https://ksma.elpub.ru/jour/article/view/667
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author V. I. KONONENKO
O. I. KIT
E. F. KOMAROVA
A. Yu. MAKSIMOV
V. V. POZDNYAKOVA
I. A. NOVIKOVA
A. A. DEMIDOVA
author_facet V. I. KONONENKO
O. I. KIT
E. F. KOMAROVA
A. Yu. MAKSIMOV
V. V. POZDNYAKOVA
I. A. NOVIKOVA
A. A. DEMIDOVA
author_sort V. I. KONONENKO
collection DOAJ
description While studying the expression of transcription, neoangiogenesis and apoptosis factors in the tumour tissue and oral fluid of 141 patients with oral mucosa cancer T1-3N0-2M0, it was shown that oral mucosa cancer progression combined with postoperative purulent inflammatory complications were associated with a high level of transcription factors, enhanced translocation of hypoxia-inducible factor-1б in the core, high expression of vascular endothelial growth factor and activation of apoptosis in the tumour tissue. The revealed changes in the underlying disease progression have a reasonably greater severity.
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spelling doaj.art-38338331195e45a88ea7127fb6abd1c12024-02-25T10:57:19ZrusMinistry of Healthcare of the Russian Federation. “Kuban State Medical University”Кубанский научный медицинский вестник1608-62282541-95442017-05-0111646810.25207/1608-6228-2017-1-64-68661EVALUATION OF THE EXPRESSION OF TRANSCRIPTION, NEOANGIOGENESIS AND APOPTOSIS FACTORS IN CASE OF POSTOPERATIVE COMPLICATIONS IN PATIENTS WITH DIFFERENT PROGRESSION OF ORAL MUCOSA CANCERV. I. KONONENKO0O. I. KIT1E. F. KOMAROVA2A. Yu. MAKSIMOV3V. V. POZDNYAKOVA4I. A. NOVIKOVA5A. A. DEMIDOVA6Rostov Research Institute of OncologyRostov Research Institute of OncologyRostov Research Institute of OncologyRostov Research Institute of OncologyRostov Research Institute of OncologyRostov Research Institute of OncologyRostov Research Institute of OncologyWhile studying the expression of transcription, neoangiogenesis and apoptosis factors in the tumour tissue and oral fluid of 141 patients with oral mucosa cancer T1-3N0-2M0, it was shown that oral mucosa cancer progression combined with postoperative purulent inflammatory complications were associated with a high level of transcription factors, enhanced translocation of hypoxia-inducible factor-1б in the core, high expression of vascular endothelial growth factor and activation of apoptosis in the tumour tissue. The revealed changes in the underlying disease progression have a reasonably greater severity.https://ksma.elpub.ru/jour/article/view/667oral mucosa cancertranscription factorsvegfapoptosistumour tissueoral fluid
spellingShingle V. I. KONONENKO
O. I. KIT
E. F. KOMAROVA
A. Yu. MAKSIMOV
V. V. POZDNYAKOVA
I. A. NOVIKOVA
A. A. DEMIDOVA
EVALUATION OF THE EXPRESSION OF TRANSCRIPTION, NEOANGIOGENESIS AND APOPTOSIS FACTORS IN CASE OF POSTOPERATIVE COMPLICATIONS IN PATIENTS WITH DIFFERENT PROGRESSION OF ORAL MUCOSA CANCER
Кубанский научный медицинский вестник
oral mucosa cancer
transcription factors
vegf
apoptosis
tumour tissue
oral fluid
title EVALUATION OF THE EXPRESSION OF TRANSCRIPTION, NEOANGIOGENESIS AND APOPTOSIS FACTORS IN CASE OF POSTOPERATIVE COMPLICATIONS IN PATIENTS WITH DIFFERENT PROGRESSION OF ORAL MUCOSA CANCER
title_full EVALUATION OF THE EXPRESSION OF TRANSCRIPTION, NEOANGIOGENESIS AND APOPTOSIS FACTORS IN CASE OF POSTOPERATIVE COMPLICATIONS IN PATIENTS WITH DIFFERENT PROGRESSION OF ORAL MUCOSA CANCER
title_fullStr EVALUATION OF THE EXPRESSION OF TRANSCRIPTION, NEOANGIOGENESIS AND APOPTOSIS FACTORS IN CASE OF POSTOPERATIVE COMPLICATIONS IN PATIENTS WITH DIFFERENT PROGRESSION OF ORAL MUCOSA CANCER
title_full_unstemmed EVALUATION OF THE EXPRESSION OF TRANSCRIPTION, NEOANGIOGENESIS AND APOPTOSIS FACTORS IN CASE OF POSTOPERATIVE COMPLICATIONS IN PATIENTS WITH DIFFERENT PROGRESSION OF ORAL MUCOSA CANCER
title_short EVALUATION OF THE EXPRESSION OF TRANSCRIPTION, NEOANGIOGENESIS AND APOPTOSIS FACTORS IN CASE OF POSTOPERATIVE COMPLICATIONS IN PATIENTS WITH DIFFERENT PROGRESSION OF ORAL MUCOSA CANCER
title_sort evaluation of the expression of transcription neoangiogenesis and apoptosis factors in case of postoperative complications in patients with different progression of oral mucosa cancer
topic oral mucosa cancer
transcription factors
vegf
apoptosis
tumour tissue
oral fluid
url https://ksma.elpub.ru/jour/article/view/667
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