Comparative study to analyze the incidence of sore throat, cough, and hoarseness of voice after general anesthesia with the use of topical benzydamine hydrochloride and 2% lignocaine gel with placebo

Background: Postoperative sore throat (POST) is the most common airway-related complaint of patients after endotracheal intubation. Postextubation coughing during emergence from general anesthesia (GA) is an important problem. Objectives: To compare the effects of topical benzydamine hydrochloride a...

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Main Authors: Vangipuram Raghava Chari, Arnab Paul
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:Medical Journal of Dr. D.Y. Patil University
Subjects:
Online Access:http://www.mjdrdypu.org/article.asp?issn=0975-2870;year=2016;volume=9;issue=1;spage=61;epage=65;aulast=Chari
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author Vangipuram Raghava Chari
Arnab Paul
author_facet Vangipuram Raghava Chari
Arnab Paul
author_sort Vangipuram Raghava Chari
collection DOAJ
description Background: Postoperative sore throat (POST) is the most common airway-related complaint of patients after endotracheal intubation. Postextubation coughing during emergence from general anesthesia (GA) is an important problem. Objectives: To compare the effects of topical benzydamine hydrochloride and 2% lignocaine on reducing the incidence and severity of POST, hoarseness, and coughing after general endotracheal anesthesia. Materials and Methods: Patients were randomly allocated into three groups of 30 patients each. In Group B (topical benzydamine hydrochloride), Group L (2% lignocaine gel), Group N (normal saline) was applied to the cuffed endotracheal tube (ETT) before intubation. Results: The trend of the severity of sore throat, hoarseness of voice, and cough during the first 24 h after the GA in benzydamine recipients was significantly lower than the other two groups (P < 0.05). Conclusions: It was observed that the incidence of POST, hoarseness of voice, and cough was significantly less when cuff of ETT was lubricated with topical benzydamine hydrochloride as compared with 2% lignocaine gel.
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spelling doaj.art-3836fc7c0197465d883656da410f3c172022-12-21T19:46:56ZengWolters Kluwer Medknow PublicationsMedical Journal of Dr. D.Y. Patil University0975-28702016-01-0191616510.4103/0975-2870.167972Comparative study to analyze the incidence of sore throat, cough, and hoarseness of voice after general anesthesia with the use of topical benzydamine hydrochloride and 2% lignocaine gel with placeboVangipuram Raghava ChariArnab PaulBackground: Postoperative sore throat (POST) is the most common airway-related complaint of patients after endotracheal intubation. Postextubation coughing during emergence from general anesthesia (GA) is an important problem. Objectives: To compare the effects of topical benzydamine hydrochloride and 2% lignocaine on reducing the incidence and severity of POST, hoarseness, and coughing after general endotracheal anesthesia. Materials and Methods: Patients were randomly allocated into three groups of 30 patients each. In Group B (topical benzydamine hydrochloride), Group L (2% lignocaine gel), Group N (normal saline) was applied to the cuffed endotracheal tube (ETT) before intubation. Results: The trend of the severity of sore throat, hoarseness of voice, and cough during the first 24 h after the GA in benzydamine recipients was significantly lower than the other two groups (P < 0.05). Conclusions: It was observed that the incidence of POST, hoarseness of voice, and cough was significantly less when cuff of ETT was lubricated with topical benzydamine hydrochloride as compared with 2% lignocaine gel.http://www.mjdrdypu.org/article.asp?issn=0975-2870;year=2016;volume=9;issue=1;spage=61;epage=65;aulast=Chari2% lignocaine gelhoarseness of voicesore throattopical benzydamine
spellingShingle Vangipuram Raghava Chari
Arnab Paul
Comparative study to analyze the incidence of sore throat, cough, and hoarseness of voice after general anesthesia with the use of topical benzydamine hydrochloride and 2% lignocaine gel with placebo
Medical Journal of Dr. D.Y. Patil University
2% lignocaine gel
hoarseness of voice
sore throat
topical benzydamine
title Comparative study to analyze the incidence of sore throat, cough, and hoarseness of voice after general anesthesia with the use of topical benzydamine hydrochloride and 2% lignocaine gel with placebo
title_full Comparative study to analyze the incidence of sore throat, cough, and hoarseness of voice after general anesthesia with the use of topical benzydamine hydrochloride and 2% lignocaine gel with placebo
title_fullStr Comparative study to analyze the incidence of sore throat, cough, and hoarseness of voice after general anesthesia with the use of topical benzydamine hydrochloride and 2% lignocaine gel with placebo
title_full_unstemmed Comparative study to analyze the incidence of sore throat, cough, and hoarseness of voice after general anesthesia with the use of topical benzydamine hydrochloride and 2% lignocaine gel with placebo
title_short Comparative study to analyze the incidence of sore throat, cough, and hoarseness of voice after general anesthesia with the use of topical benzydamine hydrochloride and 2% lignocaine gel with placebo
title_sort comparative study to analyze the incidence of sore throat cough and hoarseness of voice after general anesthesia with the use of topical benzydamine hydrochloride and 2 lignocaine gel with placebo
topic 2% lignocaine gel
hoarseness of voice
sore throat
topical benzydamine
url http://www.mjdrdypu.org/article.asp?issn=0975-2870;year=2016;volume=9;issue=1;spage=61;epage=65;aulast=Chari
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AT arnabpaul comparativestudytoanalyzetheincidenceofsorethroatcoughandhoarsenessofvoiceaftergeneralanesthesiawiththeuseoftopicalbenzydaminehydrochlorideand2lignocainegelwithplacebo