Bis-Hydrazonoyl chloride as precursors
A series of novel bis-pyrazole, bis(imidazo[1,2-b][1,2,4]triazole) and bis(imidazo[1,2-a]benzimidazole) derivatives were synthesized via bis-hydrazonoyl chloride. Structures of the synthesized compounds were elucidated by means of IR, 1H NMR and mass spectral data. The biological activity of the new...
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| Format: | Article |
| Language: | English |
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Elsevier
2017-05-01
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| Series: | Arabian Journal of Chemistry |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1878535213004103 |
| _version_ | 1819101247008931840 |
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| author | Nabila Abdelshafy Kheder Thoraya Abdel Reheem Farghaly |
| author_facet | Nabila Abdelshafy Kheder Thoraya Abdel Reheem Farghaly |
| author_sort | Nabila Abdelshafy Kheder |
| collection | DOAJ |
| description | A series of novel bis-pyrazole, bis(imidazo[1,2-b][1,2,4]triazole) and bis(imidazo[1,2-a]benzimidazole) derivatives were synthesized via bis-hydrazonoyl chloride. Structures of the synthesized compounds were elucidated by means of IR, 1H NMR and mass spectral data. The biological activity of the newly synthesized compounds was examined and some of them were found to possess antimicrobial and anticancer activities. |
| first_indexed | 2024-12-22T01:15:38Z |
| format | Article |
| id | doaj.art-3838fae76eec4ecfa3d1c96917564170 |
| institution | Directory Open Access Journal |
| issn | 1878-5352 |
| language | English |
| last_indexed | 2024-12-22T01:15:38Z |
| publishDate | 2017-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Arabian Journal of Chemistry |
| spelling | doaj.art-3838fae76eec4ecfa3d1c969175641702022-12-21T18:43:53ZengElsevierArabian Journal of Chemistry1878-53522017-05-0110S2S3007S301410.1016/j.arabjc.2013.11.040Bis-Hydrazonoyl chloride as precursorsNabila Abdelshafy Kheder0Thoraya Abdel Reheem Farghaly1Department of Chemistry, Faculty of Science, Cairo University, Giza 12613, EgyptDepartment of Chemistry, Faculty of Science, Cairo University, Giza 12613, EgyptA series of novel bis-pyrazole, bis(imidazo[1,2-b][1,2,4]triazole) and bis(imidazo[1,2-a]benzimidazole) derivatives were synthesized via bis-hydrazonoyl chloride. Structures of the synthesized compounds were elucidated by means of IR, 1H NMR and mass spectral data. The biological activity of the newly synthesized compounds was examined and some of them were found to possess antimicrobial and anticancer activities.http://www.sciencedirect.com/science/article/pii/S1878535213004103bis-Hydrazonoyl chloridebis-PyrazolesNucleophilic addition reactionAntimicrobial activityAnticancer activity |
| spellingShingle | Nabila Abdelshafy Kheder Thoraya Abdel Reheem Farghaly Bis-Hydrazonoyl chloride as precursors Arabian Journal of Chemistry bis-Hydrazonoyl chloride bis-Pyrazoles Nucleophilic addition reaction Antimicrobial activity Anticancer activity |
| title | Bis-Hydrazonoyl chloride as precursors |
| title_full | Bis-Hydrazonoyl chloride as precursors |
| title_fullStr | Bis-Hydrazonoyl chloride as precursors |
| title_full_unstemmed | Bis-Hydrazonoyl chloride as precursors |
| title_short | Bis-Hydrazonoyl chloride as precursors |
| title_sort | bis hydrazonoyl chloride as precursors |
| topic | bis-Hydrazonoyl chloride bis-Pyrazoles Nucleophilic addition reaction Antimicrobial activity Anticancer activity |
| url | http://www.sciencedirect.com/science/article/pii/S1878535213004103 |
| work_keys_str_mv | AT nabilaabdelshafykheder bishydrazonoylchlorideasprecursors AT thorayaabdelreheemfarghaly bishydrazonoylchlorideasprecursors |