Tardive Syndrome Is a Mysterious Phenomenon with Different Clinical Manifestations—Review
Tardive syndrome (TS) refers to persistent hyperkinetic, hypokinetic, and sensory complaints appearing after chronic neuroleptics and other dopamine receptor-blocking agents (DRBAs). It is defined as involuntary movements, often rhythmic, choreiform, or athetoid, involving the tongue, face, extremit...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-02-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/12/4/1498 |
| _version_ | 1797620185958449152 |
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| author | Samih Badarny Rima Nassar Yazid Badarny |
| author_facet | Samih Badarny Rima Nassar Yazid Badarny |
| author_sort | Samih Badarny |
| collection | DOAJ |
| description | Tardive syndrome (TS) refers to persistent hyperkinetic, hypokinetic, and sensory complaints appearing after chronic neuroleptics and other dopamine receptor-blocking agents (DRBAs). It is defined as involuntary movements, often rhythmic, choreiform, or athetoid, involving the tongue, face, extremities, and sensory urges such as akathisia and lasts for a few weeks. TS develops in association with neuroleptic medication usage for a few months at least. There is usually a delay between the initiation of the causative drug and the onset of abnormal movements. However, it was soon noted that TS can also develop early, even days or weeks after DRBAs begin. However, the longer the exposure, the greater the risk of developing TS. Tardive dyskinesia, dystonia, akathisia, tremor, and parkinsonism are frequent phenomenologies of this syndrome. |
| first_indexed | 2024-03-11T08:37:28Z |
| format | Article |
| id | doaj.art-3839b4197fdc42b1be4c5f36ef65ad1f |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-11T08:37:28Z |
| publishDate | 2023-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-3839b4197fdc42b1be4c5f36ef65ad1f2023-11-16T21:20:25ZengMDPI AGJournal of Clinical Medicine2077-03832023-02-01124149810.3390/jcm12041498Tardive Syndrome Is a Mysterious Phenomenon with Different Clinical Manifestations—ReviewSamih Badarny0Rima Nassar1Yazid Badarny2Neurology Department, Galilee Medical Center, Nahariya 221001, IsraelFaculty of Medicine, Israel Technion, Haifa 3109601, IsraelNeurosurgery Department, Rambam Medical Center, Haifa 3109601, IsraelTardive syndrome (TS) refers to persistent hyperkinetic, hypokinetic, and sensory complaints appearing after chronic neuroleptics and other dopamine receptor-blocking agents (DRBAs). It is defined as involuntary movements, often rhythmic, choreiform, or athetoid, involving the tongue, face, extremities, and sensory urges such as akathisia and lasts for a few weeks. TS develops in association with neuroleptic medication usage for a few months at least. There is usually a delay between the initiation of the causative drug and the onset of abnormal movements. However, it was soon noted that TS can also develop early, even days or weeks after DRBAs begin. However, the longer the exposure, the greater the risk of developing TS. Tardive dyskinesia, dystonia, akathisia, tremor, and parkinsonism are frequent phenomenologies of this syndrome.https://www.mdpi.com/2077-0383/12/4/1498tardive syndromephysiopathologyclinical manifestationmanagement |
| spellingShingle | Samih Badarny Rima Nassar Yazid Badarny Tardive Syndrome Is a Mysterious Phenomenon with Different Clinical Manifestations—Review Journal of Clinical Medicine tardive syndrome physiopathology clinical manifestation management |
| title | Tardive Syndrome Is a Mysterious Phenomenon with Different Clinical Manifestations—Review |
| title_full | Tardive Syndrome Is a Mysterious Phenomenon with Different Clinical Manifestations—Review |
| title_fullStr | Tardive Syndrome Is a Mysterious Phenomenon with Different Clinical Manifestations—Review |
| title_full_unstemmed | Tardive Syndrome Is a Mysterious Phenomenon with Different Clinical Manifestations—Review |
| title_short | Tardive Syndrome Is a Mysterious Phenomenon with Different Clinical Manifestations—Review |
| title_sort | tardive syndrome is a mysterious phenomenon with different clinical manifestations review |
| topic | tardive syndrome physiopathology clinical manifestation management |
| url | https://www.mdpi.com/2077-0383/12/4/1498 |
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