Docking Studies of Phthalimide Pharmacophore as a Sodium Channel Blocker

Objective(s): Recently, phthalimide derivatives were designed based on ameltolide and thalidomide as they possess a similar degree of anticonvulsant potency due to their phenytoin-like profile. The ability of phthalimide pharmacophore to interact with neuronal voltage-dependent sodium channels was s...

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Bibliographic Details
Main Authors: Maryam Iman, Atefeh Saadabadi, Asghar Davood
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2013-09-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Online Access:http://ijbms.mums.ac.ir/pdf_1684_b80800e88e0b17f9ad1b4d7de97460bd.html

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