Docking Studies of Phthalimide Pharmacophore as a Sodium Channel Blocker
Objective(s): Recently, phthalimide derivatives were designed based on ameltolide and thalidomide as they possess a similar degree of anticonvulsant potency due to their phenytoin-like profile. The ability of phthalimide pharmacophore to interact with neuronal voltage-dependent sodium channels was s...
Main Authors: | Maryam Iman, Atefeh Saadabadi, Asghar Davood |
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Format: | Article |
Language: | English |
Published: |
Mashhad University of Medical Sciences
2013-09-01
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Series: | Iranian Journal of Basic Medical Sciences |
Subjects: | |
Online Access: | http://ijbms.mums.ac.ir/pdf_1684_b80800e88e0b17f9ad1b4d7de97460bd.html |
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