Evaluating complete remission with partial hematologic recovery (CRh) as a response criterion in myelodysplastic syndromes (MDS)

Following treatment with DNMTI therapy, patients with MDS have differences in survival according to the quality of their treatment response. In this analysis, patients who achieve CRh had similar OS compared to those meeting standard “CR” criteria, which was better than the survival of those with ot...

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Main Authors: Andrew M. Brunner, Alexander Gavralidis, Najla Al Ali, Anthony Hunter, Rami Komrokji, Amer Zeidan, David A. Sallman
Format: Article
Language:English
Published: Nature Publishing Group 2022-11-01
Series:Blood Cancer Journal
Online Access:https://doi.org/10.1038/s41408-022-00748-9
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author Andrew M. Brunner
Alexander Gavralidis
Najla Al Ali
Anthony Hunter
Rami Komrokji
Amer Zeidan
David A. Sallman
author_facet Andrew M. Brunner
Alexander Gavralidis
Najla Al Ali
Anthony Hunter
Rami Komrokji
Amer Zeidan
David A. Sallman
author_sort Andrew M. Brunner
collection DOAJ
description Following treatment with DNMTI therapy, patients with MDS have differences in survival according to the quality of their treatment response. In this analysis, patients who achieve CRh had similar OS compared to those meeting standard “CR” criteria, which was better than the survival of those with other treatment responses (p < 0.0001).
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spelling doaj.art-383dd7c757d94ef89eb58a9a3c7829dc2022-12-22T03:43:03ZengNature Publishing GroupBlood Cancer Journal2044-53852022-11-0112111610.1038/s41408-022-00748-9Evaluating complete remission with partial hematologic recovery (CRh) as a response criterion in myelodysplastic syndromes (MDS)Andrew M. Brunner0Alexander Gavralidis1Najla Al Ali2Anthony Hunter3Rami Komrokji4Amer Zeidan5David A. Sallman6Massachusetts General Hospital Cancer CenterNorth Shore Medical CenterMoffitt Cancer CenterEmory UniversityMoffitt Cancer CenterYale University School of MedicineMoffitt Cancer CenterFollowing treatment with DNMTI therapy, patients with MDS have differences in survival according to the quality of their treatment response. In this analysis, patients who achieve CRh had similar OS compared to those meeting standard “CR” criteria, which was better than the survival of those with other treatment responses (p < 0.0001).https://doi.org/10.1038/s41408-022-00748-9
spellingShingle Andrew M. Brunner
Alexander Gavralidis
Najla Al Ali
Anthony Hunter
Rami Komrokji
Amer Zeidan
David A. Sallman
Evaluating complete remission with partial hematologic recovery (CRh) as a response criterion in myelodysplastic syndromes (MDS)
Blood Cancer Journal
title Evaluating complete remission with partial hematologic recovery (CRh) as a response criterion in myelodysplastic syndromes (MDS)
title_full Evaluating complete remission with partial hematologic recovery (CRh) as a response criterion in myelodysplastic syndromes (MDS)
title_fullStr Evaluating complete remission with partial hematologic recovery (CRh) as a response criterion in myelodysplastic syndromes (MDS)
title_full_unstemmed Evaluating complete remission with partial hematologic recovery (CRh) as a response criterion in myelodysplastic syndromes (MDS)
title_short Evaluating complete remission with partial hematologic recovery (CRh) as a response criterion in myelodysplastic syndromes (MDS)
title_sort evaluating complete remission with partial hematologic recovery crh as a response criterion in myelodysplastic syndromes mds
url https://doi.org/10.1038/s41408-022-00748-9
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