A Wireless Wearable Doppler Ultrasound Detects Changing Stroke Volume: Proof-of-Principle Comparison with Trans-Esophageal Echocardiography during Coronary Bypass Surgery
Background: A novel, wireless, ultrasound biosensor that adheres to the neck and measures real-time Doppler of the carotid artery may be a useful functional hemodynamic monitor. A unique experimental set-up during elective coronary artery bypass surgery is described as a means to compare the wearabl...
| প্রধান লেখক: | , , , , , , , |
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| বিন্যাস: | প্রবন্ধ |
| ভাষা: | English |
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MDPI AG
2021-12-01
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| মালা: | Bioengineering |
| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | https://www.mdpi.com/2306-5354/8/12/203 |
| _version_ | 1827674075512700928 |
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| author | Jon-Émile Stuart Kenny Geoffrey Clarke Matt Myers Mai Elfarnawany Andrew M. Eibl Joseph K. Eibl Bhanu Nalla Rony Atoui |
| author_facet | Jon-Émile Stuart Kenny Geoffrey Clarke Matt Myers Mai Elfarnawany Andrew M. Eibl Joseph K. Eibl Bhanu Nalla Rony Atoui |
| author_sort | Jon-Émile Stuart Kenny |
| collection | DOAJ |
| description | Background: A novel, wireless, ultrasound biosensor that adheres to the neck and measures real-time Doppler of the carotid artery may be a useful functional hemodynamic monitor. A unique experimental set-up during elective coronary artery bypass surgery is described as a means to compare the wearable Doppler to trans-esophageal echocardiography (TEE). Methods: A total of two representative patients were studied at baseline and during Trendelenburg position. Carotid Doppler spectra from the wearable ultrasound and TEE were synchronously captured. Areas under the receiver operator curve (AUROC) were performed to assess the accuracy of changing common carotid artery velocity time integral (ccVTI<sub>∆</sub>) at detecting a clinically significant change in stroke volume (SV<sub>∆</sub>). Results: Synchronously measuring and comparing Doppler spectra from the wearable ultrasound and TEE is feasible during Trendelenburg positioning. In two representative cardiac surgical patients, the ccVTI<sub>∆</sub> accurately detected a clinically significant SV<sub>∆</sub> with AUROCs of 0.89, 0.91, and 0.95 when single-beat, 3-consecutive beat and 10-consecutive beat averages were assessed, respectively. Conclusion: In this proof-of-principle research communication, a wearable Doppler ultrasound system is successfully compared to TEE. Preliminary data suggests that the diagnostic accuracy of carotid Doppler ultrasonography at detecting clinically significant SV<sub>∆</sub> is enhanced by averaging more cardiac cycles. |
| first_indexed | 2024-03-10T04:34:30Z |
| format | Article |
| id | doaj.art-3842646b6d304aa7964f00d2e8cbd20b |
| institution | Directory Open Access Journal |
| issn | 2306-5354 |
| language | English |
| last_indexed | 2024-03-10T04:34:30Z |
| publishDate | 2021-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Bioengineering |
| spelling | doaj.art-3842646b6d304aa7964f00d2e8cbd20b2023-11-23T03:52:16ZengMDPI AGBioengineering2306-53542021-12-0181220310.3390/bioengineering8120203A Wireless Wearable Doppler Ultrasound Detects Changing Stroke Volume: Proof-of-Principle Comparison with Trans-Esophageal Echocardiography during Coronary Bypass SurgeryJon-Émile Stuart Kenny0Geoffrey Clarke1Matt Myers2Mai Elfarnawany3Andrew M. Eibl4Joseph K. Eibl5Bhanu Nalla6Rony Atoui7Health Sciences North Research Institute, Sudbury, ON P3E 2H2, CanadaHealth Sciences North Research Institute, Sudbury, ON P3E 2H2, CanadaFlosonics Medical, 325 Front Street, Toronto, ON M5V 2Y1, CanadaFlosonics Medical, 325 Front Street, Toronto, ON M5V 2Y1, CanadaHealth Sciences North Research Institute, Sudbury, ON P3E 2H2, CanadaHealth Sciences North Research Institute, Sudbury, ON P3E 2H2, CanadaHealth Sciences North Research Institute, Sudbury, ON P3E 2H2, CanadaHealth Sciences North Research Institute, Sudbury, ON P3E 2H2, CanadaBackground: A novel, wireless, ultrasound biosensor that adheres to the neck and measures real-time Doppler of the carotid artery may be a useful functional hemodynamic monitor. A unique experimental set-up during elective coronary artery bypass surgery is described as a means to compare the wearable Doppler to trans-esophageal echocardiography (TEE). Methods: A total of two representative patients were studied at baseline and during Trendelenburg position. Carotid Doppler spectra from the wearable ultrasound and TEE were synchronously captured. Areas under the receiver operator curve (AUROC) were performed to assess the accuracy of changing common carotid artery velocity time integral (ccVTI<sub>∆</sub>) at detecting a clinically significant change in stroke volume (SV<sub>∆</sub>). Results: Synchronously measuring and comparing Doppler spectra from the wearable ultrasound and TEE is feasible during Trendelenburg positioning. In two representative cardiac surgical patients, the ccVTI<sub>∆</sub> accurately detected a clinically significant SV<sub>∆</sub> with AUROCs of 0.89, 0.91, and 0.95 when single-beat, 3-consecutive beat and 10-consecutive beat averages were assessed, respectively. Conclusion: In this proof-of-principle research communication, a wearable Doppler ultrasound system is successfully compared to TEE. Preliminary data suggests that the diagnostic accuracy of carotid Doppler ultrasonography at detecting clinically significant SV<sub>∆</sub> is enhanced by averaging more cardiac cycles.https://www.mdpi.com/2306-5354/8/12/203fluid responsivenesscarotid dopplerfunctional hemodynamic monitoringtrans-esophageal echocardiography |
| spellingShingle | Jon-Émile Stuart Kenny Geoffrey Clarke Matt Myers Mai Elfarnawany Andrew M. Eibl Joseph K. Eibl Bhanu Nalla Rony Atoui A Wireless Wearable Doppler Ultrasound Detects Changing Stroke Volume: Proof-of-Principle Comparison with Trans-Esophageal Echocardiography during Coronary Bypass Surgery Bioengineering fluid responsiveness carotid doppler functional hemodynamic monitoring trans-esophageal echocardiography |
| title | A Wireless Wearable Doppler Ultrasound Detects Changing Stroke Volume: Proof-of-Principle Comparison with Trans-Esophageal Echocardiography during Coronary Bypass Surgery |
| title_full | A Wireless Wearable Doppler Ultrasound Detects Changing Stroke Volume: Proof-of-Principle Comparison with Trans-Esophageal Echocardiography during Coronary Bypass Surgery |
| title_fullStr | A Wireless Wearable Doppler Ultrasound Detects Changing Stroke Volume: Proof-of-Principle Comparison with Trans-Esophageal Echocardiography during Coronary Bypass Surgery |
| title_full_unstemmed | A Wireless Wearable Doppler Ultrasound Detects Changing Stroke Volume: Proof-of-Principle Comparison with Trans-Esophageal Echocardiography during Coronary Bypass Surgery |
| title_short | A Wireless Wearable Doppler Ultrasound Detects Changing Stroke Volume: Proof-of-Principle Comparison with Trans-Esophageal Echocardiography during Coronary Bypass Surgery |
| title_sort | wireless wearable doppler ultrasound detects changing stroke volume proof of principle comparison with trans esophageal echocardiography during coronary bypass surgery |
| topic | fluid responsiveness carotid doppler functional hemodynamic monitoring trans-esophageal echocardiography |
| url | https://www.mdpi.com/2306-5354/8/12/203 |
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