Transdifferentiation of Human Circulating Monocytes Into Neuronal-Like Cells in 20 Days and Without Reprograming

Transdifferentiation of Human Circulating Monocytes Into Neuronal-Like Cells in 20 Days and Without Reprograming

Despite progress, our understanding of psychiatric and neurological illnesses remains poor, at least in part due to the inability to access neurons directly from patients. Currently, there are in vitro models available but significant work remains, including the search for a less invasive, inexpensi...

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Bibliographic Details
Main Authors: Alfredo Bellon, Amelie Wegener, Adam R. Lescallette, Michael Valente, Seung-Kwon Yang, Robert Gardette, Julien Matricon, Faycal Mouaffak, Paula Watts, Lene Vimeux, Jong K. Yun, Yuka Imamura Kawasawa, Gary A. Clawson, Elisabeta Blandin, Boris Chaumette, Therese M. Jay, Marie-Odile Krebs, Vincent Feuillet, Anne Hosmalin
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Molecular Neuroscience
Subjects:
stem cells
dopamine
schizophrenia
neurite
in vitro model
GABA
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2018.00323/full

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