HPA Axis Responsiveness Associates with Central Serotonin Transporter Availability in Human Obesity and Non-Obesity Controls

HPA Axis Responsiveness Associates with Central Serotonin Transporter Availability in Human Obesity and Non-Obesity Controls

Background: Alterations of hypothalamic–pituitary–adrenal (HPA) axis activity and serotonergic signaling are implicated in the pathogenesis of human obesity and may contribute to its metabolic and mental complications. The association of these systems has not been investigated in human obesity. Obje...

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Bibliographic Details
Main Authors: Christian Schinke, Michael Rullmann, Julia Luthardt, Mandy Drabe, Elisa Preller, Georg A. Becker, Marianne Patt, Ralf Regenthal, Franziska Zientek, Osama Sabri, Florian Then Bergh, Swen Hesse
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Brain Sciences
Subjects:
obesity
hypothalamic–pituitary–adrenal axis (HPA)
serotonin transporter (5-HTT)
positron emission tomography (PET)
reward
Online Access:https://www.mdpi.com/2076-3425/12/11/1430

Internet

https://www.mdpi.com/2076-3425/12/11/1430

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