Psoriasis therapy by Chinese medicine and modern agents
Abstract Psoriasis is a chronic, painful, disfiguring and non-contagious skin disease that has globally affected at least 200 million patients. In general, mild to moderate psoriasis patients will be treated by chemical drugs or Chinese medicine, while targeting systemic biological drugs have been s...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2018-03-01
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| Series: | Chinese Medicine |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s13020-018-0174-0 |
| _version_ | 1811236928669876224 |
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| author | Shikang Meng Zibei Lin Yan Wang Zhenping Wang Ping Li Ying Zheng |
| author_facet | Shikang Meng Zibei Lin Yan Wang Zhenping Wang Ping Li Ying Zheng |
| author_sort | Shikang Meng |
| collection | DOAJ |
| description | Abstract Psoriasis is a chronic, painful, disfiguring and non-contagious skin disease that has globally affected at least 200 million patients. In general, mild to moderate psoriasis patients will be treated by chemical drugs or Chinese medicine, while targeting systemic biological drugs have been successfully developed with good efficacy but high cost burden to patients with severe psoriasis. Since the underlying mechanisms of psoriasis are not well understood, in this review, psoriasis pathogenesis and clinical therapeutic principles by modern medicine and Chinese medicine are extensively described. Based on the data from the China Food and Drug Administration, the majority of chemical drugs are utilized as the topical formulations, while Chinese medicines are mainly delivered by an oral route, suggesting that the market for topical preparations of Chinese medicine to treat psoriasis is worth to exploration. Moreover, considering the unique clinical therapeutic theory and successful clinical application of Chinese medicine in the treatment of psoriasis, we believe that development of new small molecule drugs based on Chinese medicine will be a promising strategy to reduce therapeutic costs and improve safety for psoriatic patients. |
| first_indexed | 2024-04-12T12:17:36Z |
| format | Article |
| id | doaj.art-38471cc7d1b94a5aa951c3a23461cb87 |
| institution | Directory Open Access Journal |
| issn | 1749-8546 |
| language | English |
| last_indexed | 2024-04-12T12:17:36Z |
| publishDate | 2018-03-01 |
| publisher | BMC |
| record_format | Article |
| series | Chinese Medicine |
| spelling | doaj.art-38471cc7d1b94a5aa951c3a23461cb872022-12-22T03:33:23ZengBMCChinese Medicine1749-85462018-03-0113111010.1186/s13020-018-0174-0Psoriasis therapy by Chinese medicine and modern agentsShikang Meng0Zibei Lin1Yan Wang2Zhenping Wang3Ping Li4Ying Zheng5State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Science, University of MacauState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Science, University of MacauBeijing Hospital of Traditional Chinese Medicine, Affiliated with Capital Medical UniversityDepartment of Dermatology, School of Medicine, University of California, San DiegoBeijing Hospital of Traditional Chinese Medicine, Affiliated with Capital Medical UniversityState Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Science, University of MacauAbstract Psoriasis is a chronic, painful, disfiguring and non-contagious skin disease that has globally affected at least 200 million patients. In general, mild to moderate psoriasis patients will be treated by chemical drugs or Chinese medicine, while targeting systemic biological drugs have been successfully developed with good efficacy but high cost burden to patients with severe psoriasis. Since the underlying mechanisms of psoriasis are not well understood, in this review, psoriasis pathogenesis and clinical therapeutic principles by modern medicine and Chinese medicine are extensively described. Based on the data from the China Food and Drug Administration, the majority of chemical drugs are utilized as the topical formulations, while Chinese medicines are mainly delivered by an oral route, suggesting that the market for topical preparations of Chinese medicine to treat psoriasis is worth to exploration. Moreover, considering the unique clinical therapeutic theory and successful clinical application of Chinese medicine in the treatment of psoriasis, we believe that development of new small molecule drugs based on Chinese medicine will be a promising strategy to reduce therapeutic costs and improve safety for psoriatic patients.http://link.springer.com/article/10.1186/s13020-018-0174-0PsoriasisTherapyChinese medicine |
| spellingShingle | Shikang Meng Zibei Lin Yan Wang Zhenping Wang Ping Li Ying Zheng Psoriasis therapy by Chinese medicine and modern agents Chinese Medicine Psoriasis Therapy Chinese medicine |
| title | Psoriasis therapy by Chinese medicine and modern agents |
| title_full | Psoriasis therapy by Chinese medicine and modern agents |
| title_fullStr | Psoriasis therapy by Chinese medicine and modern agents |
| title_full_unstemmed | Psoriasis therapy by Chinese medicine and modern agents |
| title_short | Psoriasis therapy by Chinese medicine and modern agents |
| title_sort | psoriasis therapy by chinese medicine and modern agents |
| topic | Psoriasis Therapy Chinese medicine |
| url | http://link.springer.com/article/10.1186/s13020-018-0174-0 |
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