LC-HRMS/MS-Based Metabolomics Approaches Applied to the Detection of Antifungal Compounds and a Metabolic Dynamic Assessment of Orchidaceae

LC-HRMS/MS-Based Metabolomics Approaches Applied to the Detection of Antifungal Compounds and a Metabolic Dynamic Assessment of Orchidaceae

The liquid chromatography–mass spectrometry (LC-MS)-based metabolomics approach is a powerful technology for discovering novel biologically active molecules. In this study, we investigated the metabolic profiling of Orchidaceae species using LC-HRMS/MS data combined with chemometric methods and dere...

Full description

Bibliographic Details
Main Authors:	Gesiane S. Lima, Nerilson M. Lima, Jussara V. Roque, Deborah V. A. de Aguiar, João V. A. Oliveira, Gabriel F. dos Santos, Andrea R. Chaves, Boniek G. Vaz
Format:	Article
Language:	English
Published:	MDPI AG 2022-11-01
Series:	Molecules
Subjects:	liquid chromatography–mass spectrometry untargeted metabolomics metabolic dynamic antifungal compounds
Online Access:	https://www.mdpi.com/1420-3049/27/22/7937

Similar Items

Assessing the Effectiveness of Chemical Marker Extraction from Amazonian Plant Cupuassu (<i>Theobroma grandiflorum</i>) by PSI-HRMS/MS and LC-HRMS/MS
by: Nerilson M. Lima, et al.
Published: (2023-03-01)

In Vitro and In Vivo Toxicometabolomics of the Synthetic Cathinone PCYP Studied by Means of LC-HRMS/MS
by: Selina Hemmer, et al.
Published: (2022-12-01)

Comparison of Three Untargeted Data Processing Workflows for Evaluating LC-HRMS Metabolomics Data
by: Selina Hemmer, et al.
Published: (2020-09-01)

Comparison of Metabolomic Profiles of Organs in Mice of Different Strains Based on SPME-LC-HRMS
by: Katarzyna Burlikowska, et al.
Published: (2020-06-01)

Detection of Pork in Beef Meatballs Using LC-HRMS Based Untargeted Metabolomics and Chemometrics for Halal Authentication
by: Anjar Windarsih, et al.
Published: (2022-11-01)

LC-MS investigated as a tool to study the metabolomic characteristics of cereal fermentation
by: Rishibha Gupta, et al.
Published: (2024-06-01)

JPA: joint metabolic feature extraction increases the depth of chemical coverage for LC-MS-based metabolomics and exposomics
by: Guo, Jian, et al.
Published: (2023)

Discovery of Urinary Biomarkers of Seaweed Intake Using Untargeted LC–MS Metabolomics in a Three-Way Cross-Over Human Study
by: Muyao Xi, et al.
Published: (2020-12-01)

Discovery of potential biomarkers for osteoporosis using LC/GC−MS metabolomic methods
by: Yahui Wu, et al.
Published: (2024-01-01)

Enhanced Metabolome Coverage and Evaluation of Matrix Effects by the Use of Experimental-Condition-Matched <sup>13</sup>C-Labeled Biological Samples in Isotope-Assisted LC-HRMS Metabolomics
by: Asja Ćeranić, et al.
Published: (2020-10-01)

LC-MS based untargeted metabolomics studies of the metabolic response of Ginkgo biloba extract on arsenism patients
by: Weiwei Li, et al.
Published: (2024-04-01)

LC-MS Analysis and Antifungal Activity of <i>Turnera subulata</i> Sm.
by: Jacqueline Cosmo Andrade-Pinheiro, et al.
Published: (2023-01-01)

A Python-Based Pipeline for Preprocessing LC–MS Data for Untargeted Metabolomics Workflows
by: Gabriel Riquelme, et al.
Published: (2020-10-01)

UHPLC-HRMS-Based Untargeted Lipidomics Reveal Mechanism of Antifungal Activity of Carvacrol against <i>Aspergillus flavus</i>
by: Chenling Qu, et al.
Published: (2021-12-01)

His-Ala-Phe-Lys peptide from Burkholderia arboris possesses antifungal activity
by: Huajie Zhu, et al.
Published: (2022-12-01)

Untargeted lipidomics approach using LC-Orbitrap HRMS to discriminate lard from beef tallow and chicken fat for the authentification of halal
by: A. Windarsih, et al.
Published: (2023-10-01)

A Metabolomic Study of <i>Epichloë</i> Endophytes for Screening Antifungal Metabolites
by: Krishni Fernando, et al.
Published: (2022-01-01)

JPA: Joint Metabolic Feature Extraction Increases the Depth of Chemical Coverage for LC-MS-Based Metabolomics and Exposomics
by: Jian Guo, et al.
Published: (2022-02-01)

Untargeted Metabolomics Approach Using UHPLC-HRMS to Unravel the Impact of Fermentation on Color and Phenolic Composition of Rosé Wines
by: Cécile Leborgne, et al.
Published: (2023-07-01)

Serum metabolic profiling of rats infected with Clonorchis sinensis using LC-MS/MS method
by: Su Han, et al.
Published: (2023-01-01)

LC–MS-Based Metabolomics Discriminates Premium from Standard Chilean cv. Cabernet Sauvignon Wines from Different Valleys
by: Vania Sáez, et al.
Published: (2021-11-01)

Analysis of metabolites of bactrain camel milk in Alxa of China before and after fermentation with fermenting agent TR1 based on untargeted LC-MS/MS based metabolomics
by: Weisheng Xu, et al.
Published: (2023-08-01)

Antifungal Effect of <i>Bacillus velezensis</i> ZN-S10 against Plant Pathogen <i>Colletotrichum changpingense</i> and Its Inhibition Mechanism
by: Qingling Ye, et al.
Published: (2023-11-01)

Time Dependency of Chemodiversity and Biosynthetic Pathways: An LC-MS Metabolomic Study of Marine-Sourced Penicillium
by: Catherine Roullier, et al.
Published: (2016-05-01)

Comprehensive Peak Characterization (CPC) in Untargeted LC–MS Analysis
by: Kristian Pirttilä, et al.
Published: (2022-02-01)

Comprehensive Analysis of 11 Species of <i>Euodia</i> (Rutaceae) by Untargeted LC-IT-TOF/MS Metabolomics and In Vitro Functional Methods
by: Xuhong Yong, et al.
Published: (2024-02-01)

Untangling the Complexities of Processing and Analysis for Untargeted LC-MS Data Using Open-Source Tools
by: Elizabeth J. Parker, et al.
Published: (2023-03-01)

Development and Validation of LC-Q-TOF-MS Methodology to Determine Mycotoxin Biomarkers in Human Urine
by: Nuria Dasí-Navarro, et al.
Published: (2022-09-01)

Untargeted LC-MS Metabolomics Differentiates Between Virulent and Avirulent Clinical Strains of <i>Pseudomonas aeruginosa</i>
by: Tobias Depke, et al.
Published: (2020-07-01)

Untargeted Metabolomics Using UHPLC-HRMS Reveals Metabolic Changes of Fresh-Cut Potato during Browning Process
by: Baohong Li, et al.
Published: (2023-04-01)

Secondary or Specialized Metabolites, or Natural Products: A Case Study of Untargeted LC–QTOF Auto-MS/MS Analysis
by: Franz Hadacek
Published: (2022-03-01)

Development and Application of an LC-MS/MS Untargeted Exposomics Method with a Separated Pooled Quality Control Strategy
by: Gianfranco Frigerio, et al.
Published: (2022-04-01)

Optimization of an Untargeted DART-HRMS Method Envisaging Identification of Potential Markers for Saffron Authenticity Assessment
by: Elisabetta De Angelis, et al.
Published: (2021-05-01)

LC-DAD–ESI-MS/MS and NMR Analysis of Conifer Wood Specialized Metabolites
by: Andrzej Patyra, et al.
Published: (2022-10-01)

GC-MS Metabolomics and Antifungal Characteristics of Autochthonous <i>Lactobacillus</i> Strains
by: Paola Scano, et al.
Published: (2021-06-01)

LC–MS-based lipidomic analysis of liver tissue sample from spontaneously hypertensive rats treated with extract hawthorn fruits
by: Luping Sun, et al.
Published: (2022-08-01)

LC-MS metabolomics profiling of Salvia aegyptiaca L. and S. lanigera Poir. with the antimicrobial properties of their extracts
by: Alyaa Nasr, et al.
Published: (2023-06-01)

Hopomics: <i>Humulus lupulus</i> Brewing Cultivars Classification Based on LC-MS Profiling and Nested Feature Selection
by: Yuriy Andreevich Ikhalaynen, et al.
Published: (2022-10-01)

Cyclic Tetrapeptides with Synergistic Antifungal Activity from the Fungus <i>Aspergillus westerdijkiae</i> Using LC-MS/MS-Based Molecular Networking
by: Junjie Han, et al.
Published: (2022-01-01)

Investigation of Bemethyl Biotransformation Pathways by Combination of LC–MS/HRMS and In Silico Methods
by: Daria A. Belinskaia, et al.
Published: (2021-08-01)