Molecular Targets of Active Anticancer Compounds Derived from Marine Sources
Over the past decades, a number of novel compounds, which are produced in the marine environment, have been found to exhibit the anticancer effects. This review focuses on molecular targets of marine-derived anticancer candidates in clinical and preclinical studies. They are kinases, transcription f...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2018-05-01
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| Series: | Marine Drugs |
| Subjects: | |
| Online Access: | http://www.mdpi.com/1660-3397/16/5/175 |
| _version_ | 1811306672294985728 |
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| author | Xiaoping Song Ying Xiong Xin Qi Wei Tang Jiajia Dai Qianqun Gu Jing Li |
| author_facet | Xiaoping Song Ying Xiong Xin Qi Wei Tang Jiajia Dai Qianqun Gu Jing Li |
| author_sort | Xiaoping Song |
| collection | DOAJ |
| description | Over the past decades, a number of novel compounds, which are produced in the marine environment, have been found to exhibit the anticancer effects. This review focuses on molecular targets of marine-derived anticancer candidates in clinical and preclinical studies. They are kinases, transcription factors, histone deacetylase, the ubiquitin-proteasome system, and so on. Specific emphasis of this review paper is to provide information on the optimization of new target compounds for future research and development of anticancer drugs, based on the identification of structures of these target molecules and parallel compounds. |
| first_indexed | 2024-04-13T08:49:40Z |
| format | Article |
| id | doaj.art-384878ee9a5b4c53a3449f2663e281d4 |
| institution | Directory Open Access Journal |
| issn | 1660-3397 |
| language | English |
| last_indexed | 2024-04-13T08:49:40Z |
| publishDate | 2018-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Marine Drugs |
| spelling | doaj.art-384878ee9a5b4c53a3449f2663e281d42022-12-22T02:53:32ZengMDPI AGMarine Drugs1660-33972018-05-0116517510.3390/md16050175md16050175Molecular Targets of Active Anticancer Compounds Derived from Marine SourcesXiaoping Song0Ying Xiong1Xin Qi2Wei Tang3Jiajia Dai4Qianqun Gu5Jing Li6Key Laboratory of Marine Drugs of Minister of Education of China, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266071, ChinaKey Laboratory of Marine Drugs of Minister of Education of China, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266071, ChinaKey Laboratory of Marine Drugs of Minister of Education of China, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266071, ChinaKey Laboratory of Marine Drugs of Minister of Education of China, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266071, ChinaKey Laboratory of Marine Drugs of Minister of Education of China, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266071, ChinaKey Laboratory of Marine Drugs of Minister of Education of China, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266071, ChinaKey Laboratory of Marine Drugs of Minister of Education of China, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266071, ChinaOver the past decades, a number of novel compounds, which are produced in the marine environment, have been found to exhibit the anticancer effects. This review focuses on molecular targets of marine-derived anticancer candidates in clinical and preclinical studies. They are kinases, transcription factors, histone deacetylase, the ubiquitin-proteasome system, and so on. Specific emphasis of this review paper is to provide information on the optimization of new target compounds for future research and development of anticancer drugs, based on the identification of structures of these target molecules and parallel compounds.http://www.mdpi.com/1660-3397/16/5/175marine sourcesanticancer compoundsmolecular targets |
| spellingShingle | Xiaoping Song Ying Xiong Xin Qi Wei Tang Jiajia Dai Qianqun Gu Jing Li Molecular Targets of Active Anticancer Compounds Derived from Marine Sources Marine Drugs marine sources anticancer compounds molecular targets |
| title | Molecular Targets of Active Anticancer Compounds Derived from Marine Sources |
| title_full | Molecular Targets of Active Anticancer Compounds Derived from Marine Sources |
| title_fullStr | Molecular Targets of Active Anticancer Compounds Derived from Marine Sources |
| title_full_unstemmed | Molecular Targets of Active Anticancer Compounds Derived from Marine Sources |
| title_short | Molecular Targets of Active Anticancer Compounds Derived from Marine Sources |
| title_sort | molecular targets of active anticancer compounds derived from marine sources |
| topic | marine sources anticancer compounds molecular targets |
| url | http://www.mdpi.com/1660-3397/16/5/175 |
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