Comparison between Quantitative Computed Tomography and Dual-Energy X-Ray Absorptiometry in the Detection of Osteoporosis in Postmenopausal Women

Background: Osteoporosis is denoted by low bone mass and microarchitectural breakdown of bone tissue, directing to increased fracture risk and bone fragility. Fractures may lead to a decreased quality of life and increased medical costs. Thus, osteoporosis is widely considered a significant health...

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Main Authors: Abdulsattar Hameed Hammood, Sahar Basim Ahmed, Qays Ahmed Hassan
Format: Article
Language:English
Published: University of Baghdad/ Al-Kindy College of Medicine 2023-04-01
Series:مجله كليه طب الكندي
Subjects:
Online Access:https://jkmc.uobaghdad.edu.iq/index.php/MEDICAL/article/view/864
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author Abdulsattar Hameed Hammood
Sahar Basim Ahmed
Qays Ahmed Hassan
author_facet Abdulsattar Hameed Hammood
Sahar Basim Ahmed
Qays Ahmed Hassan
author_sort Abdulsattar Hameed Hammood
collection DOAJ
description Background: Osteoporosis is denoted by low bone mass and microarchitectural breakdown of bone tissue, directing to increased fracture risk and bone fragility. Fractures may lead to a decreased quality of life and increased medical costs. Thus, osteoporosis is widely considered a significant health concern. Objective. This study aimed to compare quantitative computed tomography (QCT) and dual-energy X-Ray absorptiometry (DXA) to detect osteoporosis in postmenopausal women. Subjects and Methods. We measured spinal volumetric bone mineral density (BMD) with QCT and areal spinal and hip BMD with DXA in 164 postmenopausal women. We calculated the osteopenia and osteoporosis detection rate for the two methods. The difference between these rates for DXA versus QCT was analyzed using the chi-square test. Results. The detection rate of osteoporosis was 57.9% for QCT and 50.6% for DXA (significant difference, p=0.002). At the same time, the detection rate of osteopenia was 36.6% for QCT and 31.7% for DXA (significant difference, p=0.002). Conclusions. Quantitative CT bone densitometry is an excellent tool for the evaluation of BMD. It is more sensitive than DXA for detecting osteoporosis in postmenopausal women.
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spelling doaj.art-384c37f559c64cedb57491144e2659162023-05-03T21:57:12ZengUniversity of Baghdad/ Al-Kindy College of Medicineمجله كليه طب الكندي1810-95432521-43652023-04-0119110.47723/kcmj.v19i1.864Comparison between Quantitative Computed Tomography and Dual-Energy X-Ray Absorptiometry in the Detection of Osteoporosis in Postmenopausal Women Abdulsattar Hameed HammoodSahar Basim AhmedQays Ahmed Hassan0Alkindy college of medicine Background: Osteoporosis is denoted by low bone mass and microarchitectural breakdown of bone tissue, directing to increased fracture risk and bone fragility. Fractures may lead to a decreased quality of life and increased medical costs. Thus, osteoporosis is widely considered a significant health concern. Objective. This study aimed to compare quantitative computed tomography (QCT) and dual-energy X-Ray absorptiometry (DXA) to detect osteoporosis in postmenopausal women. Subjects and Methods. We measured spinal volumetric bone mineral density (BMD) with QCT and areal spinal and hip BMD with DXA in 164 postmenopausal women. We calculated the osteopenia and osteoporosis detection rate for the two methods. The difference between these rates for DXA versus QCT was analyzed using the chi-square test. Results. The detection rate of osteoporosis was 57.9% for QCT and 50.6% for DXA (significant difference, p=0.002). At the same time, the detection rate of osteopenia was 36.6% for QCT and 31.7% for DXA (significant difference, p=0.002). Conclusions. Quantitative CT bone densitometry is an excellent tool for the evaluation of BMD. It is more sensitive than DXA for detecting osteoporosis in postmenopausal women. https://jkmc.uobaghdad.edu.iq/index.php/MEDICAL/article/view/864Postmenopausal osteoporosisquantitative computed tomographydual-energy X-Ray absorptiometry
spellingShingle Abdulsattar Hameed Hammood
Sahar Basim Ahmed
Qays Ahmed Hassan
Comparison between Quantitative Computed Tomography and Dual-Energy X-Ray Absorptiometry in the Detection of Osteoporosis in Postmenopausal Women
مجله كليه طب الكندي
Postmenopausal osteoporosis
quantitative computed tomography
dual-energy X-Ray absorptiometry
title Comparison between Quantitative Computed Tomography and Dual-Energy X-Ray Absorptiometry in the Detection of Osteoporosis in Postmenopausal Women
title_full Comparison between Quantitative Computed Tomography and Dual-Energy X-Ray Absorptiometry in the Detection of Osteoporosis in Postmenopausal Women
title_fullStr Comparison between Quantitative Computed Tomography and Dual-Energy X-Ray Absorptiometry in the Detection of Osteoporosis in Postmenopausal Women
title_full_unstemmed Comparison between Quantitative Computed Tomography and Dual-Energy X-Ray Absorptiometry in the Detection of Osteoporosis in Postmenopausal Women
title_short Comparison between Quantitative Computed Tomography and Dual-Energy X-Ray Absorptiometry in the Detection of Osteoporosis in Postmenopausal Women
title_sort comparison between quantitative computed tomography and dual energy x ray absorptiometry in the detection of osteoporosis in postmenopausal women
topic Postmenopausal osteoporosis
quantitative computed tomography
dual-energy X-Ray absorptiometry
url https://jkmc.uobaghdad.edu.iq/index.php/MEDICAL/article/view/864
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