Therapeutic Values of Myeloid-Derived Suppressor Cells in Hepatocellular Carcinoma: Facts and Hopes

Therapeutic Values of Myeloid-Derived Suppressor Cells in Hepatocellular Carcinoma: Facts and Hopes

One of the major challenges in hepatocellular carcinoma (HCC) treatment is drug resistance and low responsiveness to systemic therapies, partly due to insufficient T cell infiltration. Myeloid-derived suppressor cells (MDSCs) are immature marrow-derived cell populations with heterogeneity and immuno...

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Bibliographic Details
Main Authors: Yijun Wang, Tongyue Zhang, Mengyu Sun, Xiaoyu Ji, Meng Xie, Wenjie Huang, Limin Xia
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Cancers
Subjects:
myeloid-derived suppressor cells
hepatocellular carcinoma
HCC
combination therapy
immunotherapy
tumor microenvironment
Online Access:https://www.mdpi.com/2072-6694/13/20/5127

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