Dynamic Calcium Release From Endoplasmic Reticulum Mediated by Ryanodine Receptor 3 Is Crucial for Oligodendroglial Differentiation

Dynamic Calcium Release From Endoplasmic Reticulum Mediated by Ryanodine Receptor 3 Is Crucial for Oligodendroglial Differentiation

Increased intracellular Ca2+ in oligodendrocyte progenitor cells (OPCs) is important to initiate their differentiation, but the intracellular Ca2+ channel involved in this process remains unclear. As a Ca2+-induced Ca2+ release (CICR) channel that mediates endoplasmic reticulum (ER) Ca2+ release, th...

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Bibliographic Details
Main Authors: Tao Li, Lingyun Wang, Teng Ma, Shouyu Wang, Jianqin Niu, Hongli Li, Lan Xiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Molecular Neuroscience
Subjects:
oligodendrocyte progenitor cells (OPCs)
oligodendrocytes (OLs)
ryanodine receptor 3 (RyR3)
Ca2+ release
differentiation
caffeine
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2018.00162/full

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