Interaction-Induced Structural Transformations in Polysaccharide and Protein-Polysaccharide Gels as Functional Basis for Novel Soft-Matter: A Case of Carrageenans
Biocompatible, nontoxic, and biodegradable polysaccharides are considered as a promising base for bio-inspired materials, applicable as scaffolds in regenerative medicine, coatings in drug delivery systems, etc. The tunable macroscopic properties of gels should meet case-dependent requirements. The...
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Format: | Article |
Language: | English |
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MDPI AG
2022-05-01
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Series: | Gels |
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Online Access: | https://www.mdpi.com/2310-2861/8/5/287 |
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author | Olga N. Makshakova Yuriy F. Zuev |
author_facet | Olga N. Makshakova Yuriy F. Zuev |
author_sort | Olga N. Makshakova |
collection | DOAJ |
description | Biocompatible, nontoxic, and biodegradable polysaccharides are considered as a promising base for bio-inspired materials, applicable as scaffolds in regenerative medicine, coatings in drug delivery systems, etc. The tunable macroscopic properties of gels should meet case-dependent requirements. The admixture of proteins to polysaccharides and their coupling in more sophisticated structures opens an avenue for gel property tuning via physical cross-linking of components and the modification of gel network structure. In this review recent success in the conformational studies of binary protein–polysaccharide gels is summarized with the main focus upon carrageenans. Future perspectives and challenges in rational design of novel polysaccharide-based materials are outlined. |
first_indexed | 2024-03-10T03:51:03Z |
format | Article |
id | doaj.art-38557f52929e48568754411ad993e611 |
institution | Directory Open Access Journal |
issn | 2310-2861 |
language | English |
last_indexed | 2024-03-10T03:51:03Z |
publishDate | 2022-05-01 |
publisher | MDPI AG |
record_format | Article |
series | Gels |
spelling | doaj.art-38557f52929e48568754411ad993e6112023-11-23T11:07:38ZengMDPI AGGels2310-28612022-05-018528710.3390/gels8050287Interaction-Induced Structural Transformations in Polysaccharide and Protein-Polysaccharide Gels as Functional Basis for Novel Soft-Matter: A Case of CarrageenansOlga N. Makshakova0Yuriy F. Zuev1Kazan Institute of Biochemistry and Biophysics, FRC Kazan Scientific Center of RAS, Lobachevsky Str., 2/31, 420111 Kazan, RussiaKazan Institute of Biochemistry and Biophysics, FRC Kazan Scientific Center of RAS, Lobachevsky Str., 2/31, 420111 Kazan, RussiaBiocompatible, nontoxic, and biodegradable polysaccharides are considered as a promising base for bio-inspired materials, applicable as scaffolds in regenerative medicine, coatings in drug delivery systems, etc. The tunable macroscopic properties of gels should meet case-dependent requirements. The admixture of proteins to polysaccharides and their coupling in more sophisticated structures opens an avenue for gel property tuning via physical cross-linking of components and the modification of gel network structure. In this review recent success in the conformational studies of binary protein–polysaccharide gels is summarized with the main focus upon carrageenans. Future perspectives and challenges in rational design of novel polysaccharide-based materials are outlined.https://www.mdpi.com/2310-2861/8/5/287protein–polysaccharide gelsκ-carrageenangalactanstructurecrosslinkingFTIR-spectroscopy |
spellingShingle | Olga N. Makshakova Yuriy F. Zuev Interaction-Induced Structural Transformations in Polysaccharide and Protein-Polysaccharide Gels as Functional Basis for Novel Soft-Matter: A Case of Carrageenans Gels protein–polysaccharide gels κ-carrageenan galactan structure crosslinking FTIR-spectroscopy |
title | Interaction-Induced Structural Transformations in Polysaccharide and Protein-Polysaccharide Gels as Functional Basis for Novel Soft-Matter: A Case of Carrageenans |
title_full | Interaction-Induced Structural Transformations in Polysaccharide and Protein-Polysaccharide Gels as Functional Basis for Novel Soft-Matter: A Case of Carrageenans |
title_fullStr | Interaction-Induced Structural Transformations in Polysaccharide and Protein-Polysaccharide Gels as Functional Basis for Novel Soft-Matter: A Case of Carrageenans |
title_full_unstemmed | Interaction-Induced Structural Transformations in Polysaccharide and Protein-Polysaccharide Gels as Functional Basis for Novel Soft-Matter: A Case of Carrageenans |
title_short | Interaction-Induced Structural Transformations in Polysaccharide and Protein-Polysaccharide Gels as Functional Basis for Novel Soft-Matter: A Case of Carrageenans |
title_sort | interaction induced structural transformations in polysaccharide and protein polysaccharide gels as functional basis for novel soft matter a case of carrageenans |
topic | protein–polysaccharide gels κ-carrageenan galactan structure crosslinking FTIR-spectroscopy |
url | https://www.mdpi.com/2310-2861/8/5/287 |
work_keys_str_mv | AT olganmakshakova interactioninducedstructuraltransformationsinpolysaccharideandproteinpolysaccharidegelsasfunctionalbasisfornovelsoftmatteracaseofcarrageenans AT yuriyfzuev interactioninducedstructuraltransformationsinpolysaccharideandproteinpolysaccharidegelsasfunctionalbasisfornovelsoftmatteracaseofcarrageenans |