Interaction-Induced Structural Transformations in Polysaccharide and Protein-Polysaccharide Gels as Functional Basis for Novel Soft-Matter: A Case of Carrageenans

Biocompatible, nontoxic, and biodegradable polysaccharides are considered as a promising base for bio-inspired materials, applicable as scaffolds in regenerative medicine, coatings in drug delivery systems, etc. The tunable macroscopic properties of gels should meet case-dependent requirements. The...

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Main Authors: Olga N. Makshakova, Yuriy F. Zuev
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Gels
Subjects:
Online Access:https://www.mdpi.com/2310-2861/8/5/287
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author Olga N. Makshakova
Yuriy F. Zuev
author_facet Olga N. Makshakova
Yuriy F. Zuev
author_sort Olga N. Makshakova
collection DOAJ
description Biocompatible, nontoxic, and biodegradable polysaccharides are considered as a promising base for bio-inspired materials, applicable as scaffolds in regenerative medicine, coatings in drug delivery systems, etc. The tunable macroscopic properties of gels should meet case-dependent requirements. The admixture of proteins to polysaccharides and their coupling in more sophisticated structures opens an avenue for gel property tuning via physical cross-linking of components and the modification of gel network structure. In this review recent success in the conformational studies of binary protein–polysaccharide gels is summarized with the main focus upon carrageenans. Future perspectives and challenges in rational design of novel polysaccharide-based materials are outlined.
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spelling doaj.art-38557f52929e48568754411ad993e6112023-11-23T11:07:38ZengMDPI AGGels2310-28612022-05-018528710.3390/gels8050287Interaction-Induced Structural Transformations in Polysaccharide and Protein-Polysaccharide Gels as Functional Basis for Novel Soft-Matter: A Case of CarrageenansOlga N. Makshakova0Yuriy F. Zuev1Kazan Institute of Biochemistry and Biophysics, FRC Kazan Scientific Center of RAS, Lobachevsky Str., 2/31, 420111 Kazan, RussiaKazan Institute of Biochemistry and Biophysics, FRC Kazan Scientific Center of RAS, Lobachevsky Str., 2/31, 420111 Kazan, RussiaBiocompatible, nontoxic, and biodegradable polysaccharides are considered as a promising base for bio-inspired materials, applicable as scaffolds in regenerative medicine, coatings in drug delivery systems, etc. The tunable macroscopic properties of gels should meet case-dependent requirements. The admixture of proteins to polysaccharides and their coupling in more sophisticated structures opens an avenue for gel property tuning via physical cross-linking of components and the modification of gel network structure. In this review recent success in the conformational studies of binary protein–polysaccharide gels is summarized with the main focus upon carrageenans. Future perspectives and challenges in rational design of novel polysaccharide-based materials are outlined.https://www.mdpi.com/2310-2861/8/5/287protein–polysaccharide gelsκ-carrageenangalactanstructurecrosslinkingFTIR-spectroscopy
spellingShingle Olga N. Makshakova
Yuriy F. Zuev
Interaction-Induced Structural Transformations in Polysaccharide and Protein-Polysaccharide Gels as Functional Basis for Novel Soft-Matter: A Case of Carrageenans
Gels
protein–polysaccharide gels
κ-carrageenan
galactan
structure
crosslinking
FTIR-spectroscopy
title Interaction-Induced Structural Transformations in Polysaccharide and Protein-Polysaccharide Gels as Functional Basis for Novel Soft-Matter: A Case of Carrageenans
title_full Interaction-Induced Structural Transformations in Polysaccharide and Protein-Polysaccharide Gels as Functional Basis for Novel Soft-Matter: A Case of Carrageenans
title_fullStr Interaction-Induced Structural Transformations in Polysaccharide and Protein-Polysaccharide Gels as Functional Basis for Novel Soft-Matter: A Case of Carrageenans
title_full_unstemmed Interaction-Induced Structural Transformations in Polysaccharide and Protein-Polysaccharide Gels as Functional Basis for Novel Soft-Matter: A Case of Carrageenans
title_short Interaction-Induced Structural Transformations in Polysaccharide and Protein-Polysaccharide Gels as Functional Basis for Novel Soft-Matter: A Case of Carrageenans
title_sort interaction induced structural transformations in polysaccharide and protein polysaccharide gels as functional basis for novel soft matter a case of carrageenans
topic protein–polysaccharide gels
κ-carrageenan
galactan
structure
crosslinking
FTIR-spectroscopy
url https://www.mdpi.com/2310-2861/8/5/287
work_keys_str_mv AT olganmakshakova interactioninducedstructuraltransformationsinpolysaccharideandproteinpolysaccharidegelsasfunctionalbasisfornovelsoftmatteracaseofcarrageenans
AT yuriyfzuev interactioninducedstructuraltransformationsinpolysaccharideandproteinpolysaccharidegelsasfunctionalbasisfornovelsoftmatteracaseofcarrageenans