Correlation of Serum Uric Acid and Proteinuria in Patients with Type 2 Di-abetes Mellitus
Background: Diabetes mellitus is one of the most common and important metabolic diseases worldwide. Hperuricemia is associated with kidney damage manifested by glomerular hypertrophy and sclerosis. The aim of this study was evaluation of association between serum uric acid level and proteinuria in p...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | fas |
| Published: |
Isfahan University of Medical Sciences
2011-02-01
|
| Series: | مجله دانشکده پزشکی اصفهان |
| Subjects: | |
| Online Access: | http://jims.mui.ac.ir/index.php/jims/article/view/582 |
| _version_ | 1797762035711213568 |
|---|---|
| author | Ali Momeni Mahmood Mirhoseini Elahe Niazi |
| author_facet | Ali Momeni Mahmood Mirhoseini Elahe Niazi |
| author_sort | Ali Momeni |
| collection | DOAJ |
| description | Background: Diabetes mellitus is one of the most common and important metabolic diseases worldwide. Hperuricemia is associated with kidney damage manifested by glomerular hypertrophy and sclerosis. The aim of this study was evaluation of association between serum uric acid level and proteinuria in patients with type 2 diabetes mellitus.
Methods: A total of 140 patients (48 men and 92 women) with type 2 diabetes mellitus were enrolled in the study. Demographic criteria as age, body mass index, serum uric acid level and 24 hours urine protein were measured in these patients.
Finding: Mean of patients age was 59.8 ± 10 years. Uric acid level in patients with significant proteinuria (≥ 500 mg/24 h) and mild proteinuria (< 500 mg/24 h) were 6.70 ± 1.82 and 5.06 ± 1.46 mg/dl respectively (P < 0.001). Serum uric acid level had positive correlation with 24 hours urine protein, duration of diabetes and insulin treatment.
Conclusion: In type 2 diabetes mellitus, serum uric acid level has positive correlation with proteinuria; so uric acid maybe has a role in progression of diabetic nephropathy. |
| first_indexed | 2024-03-12T19:22:35Z |
| format | Article |
| id | doaj.art-385f65daad714afbb531e640a20e5113 |
| institution | Directory Open Access Journal |
| issn | 1027-7595 1735-854X |
| language | fas |
| last_indexed | 2024-03-12T19:22:35Z |
| publishDate | 2011-02-01 |
| publisher | Isfahan University of Medical Sciences |
| record_format | Article |
| series | مجله دانشکده پزشکی اصفهان |
| spelling | doaj.art-385f65daad714afbb531e640a20e51132023-08-02T05:03:46ZfasIsfahan University of Medical Sciencesمجله دانشکده پزشکی اصفهان1027-75951735-854X2011-02-012811812321239429Correlation of Serum Uric Acid and Proteinuria in Patients with Type 2 Di-abetes MellitusAli Momeni0Mahmood Mirhoseini1Elahe Niazi2Nephrologist, Department of Internal Medicine, Hajar Hospital, Shahrekord University of Medical Sciences, Shahrekord, IranEndocrinologst, Department of Internal Medicine, Hajar Hospital, Shahrekord University of Medical Sciences, Shahrekord, IranSayedoshohada Hospital, Shahrekord University of Medical Sciences, Shahrekord, IranBackground: Diabetes mellitus is one of the most common and important metabolic diseases worldwide. Hperuricemia is associated with kidney damage manifested by glomerular hypertrophy and sclerosis. The aim of this study was evaluation of association between serum uric acid level and proteinuria in patients with type 2 diabetes mellitus. Methods: A total of 140 patients (48 men and 92 women) with type 2 diabetes mellitus were enrolled in the study. Demographic criteria as age, body mass index, serum uric acid level and 24 hours urine protein were measured in these patients. Finding: Mean of patients age was 59.8 ± 10 years. Uric acid level in patients with significant proteinuria (≥ 500 mg/24 h) and mild proteinuria (< 500 mg/24 h) were 6.70 ± 1.82 and 5.06 ± 1.46 mg/dl respectively (P < 0.001). Serum uric acid level had positive correlation with 24 hours urine protein, duration of diabetes and insulin treatment. Conclusion: In type 2 diabetes mellitus, serum uric acid level has positive correlation with proteinuria; so uric acid maybe has a role in progression of diabetic nephropathy.http://jims.mui.ac.ir/index.php/jims/article/view/582Type 2 diabetesProteinuriaUric acid |
| spellingShingle | Ali Momeni Mahmood Mirhoseini Elahe Niazi Correlation of Serum Uric Acid and Proteinuria in Patients with Type 2 Di-abetes Mellitus مجله دانشکده پزشکی اصفهان Type 2 diabetes Proteinuria Uric acid |
| title | Correlation of Serum Uric Acid and Proteinuria in Patients with Type 2 Di-abetes Mellitus |
| title_full | Correlation of Serum Uric Acid and Proteinuria in Patients with Type 2 Di-abetes Mellitus |
| title_fullStr | Correlation of Serum Uric Acid and Proteinuria in Patients with Type 2 Di-abetes Mellitus |
| title_full_unstemmed | Correlation of Serum Uric Acid and Proteinuria in Patients with Type 2 Di-abetes Mellitus |
| title_short | Correlation of Serum Uric Acid and Proteinuria in Patients with Type 2 Di-abetes Mellitus |
| title_sort | correlation of serum uric acid and proteinuria in patients with type 2 di abetes mellitus |
| topic | Type 2 diabetes Proteinuria Uric acid |
| url | http://jims.mui.ac.ir/index.php/jims/article/view/582 |
| work_keys_str_mv | AT alimomeni correlationofserumuricacidandproteinuriainpatientswithtype2diabetesmellitus AT mahmoodmirhoseini correlationofserumuricacidandproteinuriainpatientswithtype2diabetesmellitus AT elaheniazi correlationofserumuricacidandproteinuriainpatientswithtype2diabetesmellitus |