A Case of Hypocalcaemia Due to Vitamin D Deficiency in ‘Hikikomori’ Syndrome

Objective: To describe hypocalcaemia due to vitamin D deficiency in ‘hikikomori’ syndrome. Materials and methods: A 37-year-old man with ‘hikikomori’ syndrome for a year was admitted with hypocalcaemia (serum ionic calcium 1.17 mmol/l). Serum 1,25(OH)2-vitamin D3 determined by liquid chromatography...

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Main Authors: Takahiro Miyakoshi, Mamoru Satoh, Fumio Nomura, Takao Hashimoto, Toru Aizawa
Format: Article
Language:English
Published: SMC MEDIA SRL 2017-09-01
Series:European Journal of Case Reports in Internal Medicine
Subjects:
Online Access:http://www.ejcrim.com/index.php/EJCRIM/article/view/634
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author Takahiro Miyakoshi
Mamoru Satoh
Fumio Nomura
Takao Hashimoto
Toru Aizawa
author_facet Takahiro Miyakoshi
Mamoru Satoh
Fumio Nomura
Takao Hashimoto
Toru Aizawa
author_sort Takahiro Miyakoshi
collection DOAJ
description Objective: To describe hypocalcaemia due to vitamin D deficiency in ‘hikikomori’ syndrome. Materials and methods: A 37-year-old man with ‘hikikomori’ syndrome for a year was admitted with hypocalcaemia (serum ionic calcium 1.17 mmol/l). Serum 1,25(OH)2-vitamin D3 determined by liquid chromatography–tandem mass spectrometry was depressed at 12.1 pg/ml (29.0 pmol/l) and plasma intact PTH elevated at 324 ng/l. Administration of 1 μg/day 1α(OH)-vitamin D3 and 1 g/day calcium lactate for 1 week normalized calcium and PTH, and raised 1,25(OH)2-vitamin D3 to low normal levels. Conclusion: This is the first report of hypocalcaemia due to vitamin D deficiency in a patient with ‘hikikomori’ syndrome.
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spelling doaj.art-38602d81f3c24062bb346fb7b407b3102022-12-22T03:08:08ZengSMC MEDIA SRLEuropean Journal of Case Reports in Internal Medicine2284-25942017-09-014710.12890/2017_000634224A Case of Hypocalcaemia Due to Vitamin D Deficiency in ‘Hikikomori’ SyndromeTakahiro Miyakoshi0Mamoru Satoh1Fumio Nomura2Takao Hashimoto3Toru Aizawa4Diabetes Center, Department of Neurology, Aizawa Hospital, MatsumotoDivision of Clinical Mass Spectrometry, Chiba University Hospital, ChibaDivision of Clinical Mass Spectrometry, Chiba University Hospital, ChibaDepartment of Neurology, Aizawa Hospital, MatsumotoDiabetes Center, Department of Neurology, Aizawa Hospital, MatsumotoObjective: To describe hypocalcaemia due to vitamin D deficiency in ‘hikikomori’ syndrome. Materials and methods: A 37-year-old man with ‘hikikomori’ syndrome for a year was admitted with hypocalcaemia (serum ionic calcium 1.17 mmol/l). Serum 1,25(OH)2-vitamin D3 determined by liquid chromatography–tandem mass spectrometry was depressed at 12.1 pg/ml (29.0 pmol/l) and plasma intact PTH elevated at 324 ng/l. Administration of 1 μg/day 1α(OH)-vitamin D3 and 1 g/day calcium lactate for 1 week normalized calcium and PTH, and raised 1,25(OH)2-vitamin D3 to low normal levels. Conclusion: This is the first report of hypocalcaemia due to vitamin D deficiency in a patient with ‘hikikomori’ syndrome.http://www.ejcrim.com/index.php/EJCRIM/article/view/634Hikikomori syndrome, Hypocalcemia, Hypovitaminosis D
spellingShingle Takahiro Miyakoshi
Mamoru Satoh
Fumio Nomura
Takao Hashimoto
Toru Aizawa
A Case of Hypocalcaemia Due to Vitamin D Deficiency in ‘Hikikomori’ Syndrome
European Journal of Case Reports in Internal Medicine
Hikikomori syndrome, Hypocalcemia, Hypovitaminosis D
title A Case of Hypocalcaemia Due to Vitamin D Deficiency in ‘Hikikomori’ Syndrome
title_full A Case of Hypocalcaemia Due to Vitamin D Deficiency in ‘Hikikomori’ Syndrome
title_fullStr A Case of Hypocalcaemia Due to Vitamin D Deficiency in ‘Hikikomori’ Syndrome
title_full_unstemmed A Case of Hypocalcaemia Due to Vitamin D Deficiency in ‘Hikikomori’ Syndrome
title_short A Case of Hypocalcaemia Due to Vitamin D Deficiency in ‘Hikikomori’ Syndrome
title_sort case of hypocalcaemia due to vitamin d deficiency in hikikomori syndrome
topic Hikikomori syndrome, Hypocalcemia, Hypovitaminosis D
url http://www.ejcrim.com/index.php/EJCRIM/article/view/634
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