Genotypic And Phenotypic Surveillance Of Multidrug Resistance Of Hypermucoid K. Pneumoniae Among Clinical Isolates In AL Najaf City /Iraq
Hypervirulent Klebsiella pneumoniae strains are the major cause of liver abscesses ,diabetes foot ulcers and other infections throughout Iraq, and these strains are usually antibiotics susceptible. Recently, hypervirulent K. pneumoniae isolates have emerged due to acquiring antimicrobial resista...
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| Format: | Article |
| Language: | English |
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Faculty of Science, University of Kufa
2024-01-01
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| Series: | Magazin of Al-Kufa University for Biology |
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| Online Access: | https://journal.uokufa.edu.iq/index.php/ajb/article/view/14615 |
| _version_ | 1797257236268974080 |
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| author | Ali Hussain Hmood Mahdi H.M. Alammar |
| author_facet | Ali Hussain Hmood Mahdi H.M. Alammar |
| author_sort | Ali Hussain Hmood |
| collection | DOAJ |
| description |
Hypervirulent Klebsiella pneumoniae strains are the major cause of liver abscesses ,diabetes foot ulcers and other infections throughout Iraq, and these strains are usually antibiotics susceptible. Recently, hypervirulent K. pneumoniae isolates have emerged due to acquiring antimicrobial resistance determinants or the transfer of a virulence plasmid into a classic isolates ,.Klebsiella pneumoniae is responsible for hospital- and community-acquired infections. This study aimed to determine the prevalence of hyper irulence K. pneumoniae and investigate the antibiotics resistance profile among clinical specimens at Al Najaf Hospitals in/ Iraq, and detect the genes for molecular identification of K. pneumoniae in comparison with phenotypic and biochemical methods. In total, 100 clinical specimens were collected from patients infected with K. pneumoniae, between January 2023 and May 2023 from both sexes males (38) and Females (62) with age ranged between (20-70) years. The Hypervirulent Klebsiella pneumoniae isolates were cultured on general and selective media as (Blood agar and MacConkey agar and CHROM agar), and confirmed by using Vitek-2 system. The isolates were reported with high resistance towards various types of antibiotics, especially penicillins and cephalosporins. In contrast, K. pneumoniae showed very low resistance to imipenem and amikacin. According to the results the range of multidrug-resistant K. pneumoniae isolates in this study was estimated at 100%.
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| first_indexed | 2024-04-24T22:34:26Z |
| format | Article |
| id | doaj.art-3867197302b941fb915f1f171fcab25c |
| institution | Directory Open Access Journal |
| issn | 2073-8854 2311-6544 |
| language | English |
| last_indexed | 2024-04-24T22:34:26Z |
| publishDate | 2024-01-01 |
| publisher | Faculty of Science, University of Kufa |
| record_format | Article |
| series | Magazin of Al-Kufa University for Biology |
| spelling | doaj.art-3867197302b941fb915f1f171fcab25c2024-03-19T12:39:00ZengFaculty of Science, University of KufaMagazin of Al-Kufa University for Biology2073-88542311-65442024-01-0115310.36320/ajb/v15.i3.14615Genotypic And Phenotypic Surveillance Of Multidrug Resistance Of Hypermucoid K. Pneumoniae Among Clinical Isolates In AL Najaf City /IraqAli Hussain Hmood0Mahdi H.M. Alammar1Faculty of Science,University of Kufa, IraqFaculty of Science,University of Kufa, Iraq Hypervirulent Klebsiella pneumoniae strains are the major cause of liver abscesses ,diabetes foot ulcers and other infections throughout Iraq, and these strains are usually antibiotics susceptible. Recently, hypervirulent K. pneumoniae isolates have emerged due to acquiring antimicrobial resistance determinants or the transfer of a virulence plasmid into a classic isolates ,.Klebsiella pneumoniae is responsible for hospital- and community-acquired infections. This study aimed to determine the prevalence of hyper irulence K. pneumoniae and investigate the antibiotics resistance profile among clinical specimens at Al Najaf Hospitals in/ Iraq, and detect the genes for molecular identification of K. pneumoniae in comparison with phenotypic and biochemical methods. In total, 100 clinical specimens were collected from patients infected with K. pneumoniae, between January 2023 and May 2023 from both sexes males (38) and Females (62) with age ranged between (20-70) years. The Hypervirulent Klebsiella pneumoniae isolates were cultured on general and selective media as (Blood agar and MacConkey agar and CHROM agar), and confirmed by using Vitek-2 system. The isolates were reported with high resistance towards various types of antibiotics, especially penicillins and cephalosporins. In contrast, K. pneumoniae showed very low resistance to imipenem and amikacin. According to the results the range of multidrug-resistant K. pneumoniae isolates in this study was estimated at 100%. https://journal.uokufa.edu.iq/index.php/ajb/article/view/14615K. pneumoniaehypervirulentAntibiotics resistance |
| spellingShingle | Ali Hussain Hmood Mahdi H.M. Alammar Genotypic And Phenotypic Surveillance Of Multidrug Resistance Of Hypermucoid K. Pneumoniae Among Clinical Isolates In AL Najaf City /Iraq Magazin of Al-Kufa University for Biology K. pneumoniae hypervirulent Antibiotics resistance |
| title | Genotypic And Phenotypic Surveillance Of Multidrug Resistance Of Hypermucoid K. Pneumoniae Among Clinical Isolates In AL Najaf City /Iraq |
| title_full | Genotypic And Phenotypic Surveillance Of Multidrug Resistance Of Hypermucoid K. Pneumoniae Among Clinical Isolates In AL Najaf City /Iraq |
| title_fullStr | Genotypic And Phenotypic Surveillance Of Multidrug Resistance Of Hypermucoid K. Pneumoniae Among Clinical Isolates In AL Najaf City /Iraq |
| title_full_unstemmed | Genotypic And Phenotypic Surveillance Of Multidrug Resistance Of Hypermucoid K. Pneumoniae Among Clinical Isolates In AL Najaf City /Iraq |
| title_short | Genotypic And Phenotypic Surveillance Of Multidrug Resistance Of Hypermucoid K. Pneumoniae Among Clinical Isolates In AL Najaf City /Iraq |
| title_sort | genotypic and phenotypic surveillance of multidrug resistance of hypermucoid k pneumoniae among clinical isolates in al najaf city iraq |
| topic | K. pneumoniae hypervirulent Antibiotics resistance |
| url | https://journal.uokufa.edu.iq/index.php/ajb/article/view/14615 |
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