The Assessment of Social Determinants of Health in Postsepsis Mortality and Readmission: A Scoping Review

OBJECTIVE:. To summarize knowledge and identify gaps in evidence about the relationship between social determinants of health (SDH) and postsepsis outcomes. DATA SOURCES:. We conducted a comprehensive search of PubMed/Medical Literature Analysis and Retrieval System Online, Excerpta Medica database,...

Full description

Bibliographic Details
Main Authors: Ryan S. Hilton, BS, Katrina Hauschildt, PhD, Milan Shah, MD, Marc Kowalkowski, PhD, Stephanie Taylor, MD
Format: Article
Language:English
Published: Wolters Kluwer 2022-08-01
Series:Critical Care Explorations
Online Access:http://journals.lww.com/10.1097/CCE.0000000000000722
_version_ 1817997922699051008
author Ryan S. Hilton, BS
Katrina Hauschildt, PhD
Milan Shah, MD
Marc Kowalkowski, PhD
Stephanie Taylor, MD
author_facet Ryan S. Hilton, BS
Katrina Hauschildt, PhD
Milan Shah, MD
Marc Kowalkowski, PhD
Stephanie Taylor, MD
author_sort Ryan S. Hilton, BS
collection DOAJ
description OBJECTIVE:. To summarize knowledge and identify gaps in evidence about the relationship between social determinants of health (SDH) and postsepsis outcomes. DATA SOURCES:. We conducted a comprehensive search of PubMed/Medical Literature Analysis and Retrieval System Online, Excerpta Medica database, and the Cochrane Library. STUDY SELECTION:. We identified articles that evaluated SDH as risk factors for mortality or readmission after sepsis hospitalization. Two authors independently screened and selected articles for inclusion. DATA EXTRACTION:. We dual-extracted study characteristics with specific focus on measurement, reporting, and interpretation of SDH variables. DATA SYNTHESIS:. Of 2,077 articles screened, 103 articles assessed risk factors for postsepsis mortality or readmission. Of these, 28 (27%) included at least one SDH variable. Inclusion of SDH in studies assessing postsepsis adverse outcomes increased over time. The most common SDH evaluated was race/ethnicity (n = 21, 75%), followed by payer type (n = 10, 36%), and income/wealth (n = 9, 32%). Of the studies including race/ethnicity, nine (32%) evaluated no other SDH. Only one study including race/ethnicity discussed the use of this variable as a surrogate for social disadvantage, and none specifically discussed structural racism. None of the studies specifically addressed methods to validate the accuracy of SDH or handling of missing data. Eight (29%) studies included a general statement that missing data were infrequent. Several studies reported independent associations between SDH and outcomes after sepsis discharge; however, these findings were mixed across studies. CONCLUSIONS:. Our review suggests that SDH data are underutilized and of uncertain quality in studies evaluating postsepsis adverse events. Transparent and explicit ontogenesis and data models for SDH data are urgently needed to support research and clinical applications with specific attention to advancing our understanding of the role racism and racial health inequities in postsepsis outcomes.
first_indexed 2024-04-14T02:46:45Z
format Article
id doaj.art-38696e874cb04c28a26415efd1931f0c
institution Directory Open Access Journal
issn 2639-8028
language English
last_indexed 2024-04-14T02:46:45Z
publishDate 2022-08-01
publisher Wolters Kluwer
record_format Article
series Critical Care Explorations
spelling doaj.art-38696e874cb04c28a26415efd1931f0c2022-12-22T02:16:31ZengWolters KluwerCritical Care Explorations2639-80282022-08-0148e072210.1097/CCE.0000000000000722202208000-00001The Assessment of Social Determinants of Health in Postsepsis Mortality and Readmission: A Scoping ReviewRyan S. Hilton, BS0Katrina Hauschildt, PhD1Milan Shah, MD2Marc Kowalkowski, PhD3Stephanie Taylor, MD41 Wake Forest University School of Medicine, Winston-Salem, NC.2 Center for Clinical Management and Research, VA Ann Arbor Health Care System, Ann Arbor, MI.3 Department of Internal Medicine, Carolinas Medical Center, Charlotte, NC.4 Center for Outcomes Research and Evaluation, Atrium Health, Charlotte, NC.5 Department of Internal Medicine, Wake Forest University School of Medicine Atrium Health Enterprise, Charlotte, NC.OBJECTIVE:. To summarize knowledge and identify gaps in evidence about the relationship between social determinants of health (SDH) and postsepsis outcomes. DATA SOURCES:. We conducted a comprehensive search of PubMed/Medical Literature Analysis and Retrieval System Online, Excerpta Medica database, and the Cochrane Library. STUDY SELECTION:. We identified articles that evaluated SDH as risk factors for mortality or readmission after sepsis hospitalization. Two authors independently screened and selected articles for inclusion. DATA EXTRACTION:. We dual-extracted study characteristics with specific focus on measurement, reporting, and interpretation of SDH variables. DATA SYNTHESIS:. Of 2,077 articles screened, 103 articles assessed risk factors for postsepsis mortality or readmission. Of these, 28 (27%) included at least one SDH variable. Inclusion of SDH in studies assessing postsepsis adverse outcomes increased over time. The most common SDH evaluated was race/ethnicity (n = 21, 75%), followed by payer type (n = 10, 36%), and income/wealth (n = 9, 32%). Of the studies including race/ethnicity, nine (32%) evaluated no other SDH. Only one study including race/ethnicity discussed the use of this variable as a surrogate for social disadvantage, and none specifically discussed structural racism. None of the studies specifically addressed methods to validate the accuracy of SDH or handling of missing data. Eight (29%) studies included a general statement that missing data were infrequent. Several studies reported independent associations between SDH and outcomes after sepsis discharge; however, these findings were mixed across studies. CONCLUSIONS:. Our review suggests that SDH data are underutilized and of uncertain quality in studies evaluating postsepsis adverse events. Transparent and explicit ontogenesis and data models for SDH data are urgently needed to support research and clinical applications with specific attention to advancing our understanding of the role racism and racial health inequities in postsepsis outcomes.http://journals.lww.com/10.1097/CCE.0000000000000722
spellingShingle Ryan S. Hilton, BS
Katrina Hauschildt, PhD
Milan Shah, MD
Marc Kowalkowski, PhD
Stephanie Taylor, MD
The Assessment of Social Determinants of Health in Postsepsis Mortality and Readmission: A Scoping Review
Critical Care Explorations
title The Assessment of Social Determinants of Health in Postsepsis Mortality and Readmission: A Scoping Review
title_full The Assessment of Social Determinants of Health in Postsepsis Mortality and Readmission: A Scoping Review
title_fullStr The Assessment of Social Determinants of Health in Postsepsis Mortality and Readmission: A Scoping Review
title_full_unstemmed The Assessment of Social Determinants of Health in Postsepsis Mortality and Readmission: A Scoping Review
title_short The Assessment of Social Determinants of Health in Postsepsis Mortality and Readmission: A Scoping Review
title_sort assessment of social determinants of health in postsepsis mortality and readmission a scoping review
url http://journals.lww.com/10.1097/CCE.0000000000000722
work_keys_str_mv AT ryanshiltonbs theassessmentofsocialdeterminantsofhealthinpostsepsismortalityandreadmissionascopingreview
AT katrinahauschildtphd theassessmentofsocialdeterminantsofhealthinpostsepsismortalityandreadmissionascopingreview
AT milanshahmd theassessmentofsocialdeterminantsofhealthinpostsepsismortalityandreadmissionascopingreview
AT marckowalkowskiphd theassessmentofsocialdeterminantsofhealthinpostsepsismortalityandreadmissionascopingreview
AT stephanietaylormd theassessmentofsocialdeterminantsofhealthinpostsepsismortalityandreadmissionascopingreview
AT ryanshiltonbs assessmentofsocialdeterminantsofhealthinpostsepsismortalityandreadmissionascopingreview
AT katrinahauschildtphd assessmentofsocialdeterminantsofhealthinpostsepsismortalityandreadmissionascopingreview
AT milanshahmd assessmentofsocialdeterminantsofhealthinpostsepsismortalityandreadmissionascopingreview
AT marckowalkowskiphd assessmentofsocialdeterminantsofhealthinpostsepsismortalityandreadmissionascopingreview
AT stephanietaylormd assessmentofsocialdeterminantsofhealthinpostsepsismortalityandreadmissionascopingreview