Molecular interaction of human acetylcholinesterase with trans-tephrostachin and derivatives for Alzheimer's disease

Molecular interaction of human acetylcholinesterase with trans-tephrostachin and derivatives for Alzheimer's disease

Alzheimer's disease (AD), a neurodegenerative disorder affects more than 35 million people globally. Acetylcholinesterase suppression is the common approach to enhance the well-being of AD patients by increasing the duration of acetylcholine in the cholinergic synapses. Generally, herbal second...

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Bibliographic Details
Main Authors:	Arjun Pitchai, Rajesh Kannan Rajaretinam, Rajasekar Mani, Nagasundaram Nagarajan
Format:	Article
Language:	English
Published:	Elsevier 2020-09-01
Series:	Heliyon
Subjects:	Acetylcholinesterase (AChE) Flavonoids Trans-Tephrostachin derivatives Enzyme inhibition kinetics Molecular docking and dynamics Biochemistry
Online Access:	http://www.sciencedirect.com/science/article/pii/S2405844020317734

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