Curcumin enhances the anti-cancer efficacy of paclitaxel in ovarian cancer by regulating the miR-9-5p/BRCA1 axis

Curcumin enhances the anti-cancer efficacy of paclitaxel in ovarian cancer by regulating the miR-9-5p/BRCA1 axis

Background: Patients with late-stage ovarian cancer still have a very poor prognosis due to chemotherapy resistance. Curcumin has been shown to synergistically enhance the therapeutic effects of multiple chemotherapeutic agents, but the potential involvement of curcumin in ovarian cancer is largely...

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Bibliographic Details
Main Authors: Yuwan Liu, Zhangjin Shen, Tingjia Zhu, Weiguo Lu, Yunfeng Fu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Pharmacology
Subjects:
curcumin
paclitaxel
ovarian cancer
miR-9-5p
BRCA1
synergy
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.1014933/full

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