A rare case of paediatric non-Hodgkin's lymphoma
Anaplastic large cell lymphoma (ALCL) is a rare disease accounting for 10%–15% of all non-Hodgkin's lymphomas in children. It is distinguished from other lymphomas by their anaplastic cytology and constant membrane expression of the CD30 antigen. We report a 9-year-old boy presented with a left...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2019-01-01
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| Series: | Journal of Clinical and Scientific Research |
| Subjects: | |
| Online Access: | http://www.jcsr.co.in/article.asp?issn=2277-5706;year=2019;volume=8;issue=2;spage=95;epage=97;aulast=Bhargavi |
| _version_ | 1811217884288909312 |
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| author | D Bhargavi T Kannan K L Priyadarshini V Santhosh K M Ramprahlad B Sreekanth |
| author_facet | D Bhargavi T Kannan K L Priyadarshini V Santhosh K M Ramprahlad B Sreekanth |
| author_sort | D Bhargavi |
| collection | DOAJ |
| description | Anaplastic large cell lymphoma (ALCL) is a rare disease accounting for 10%–15% of all non-Hodgkin's lymphomas in children. It is distinguished from other lymphomas by their anaplastic cytology and constant membrane expression of the CD30 antigen. We report a 9-year-old boy presented with a left calf swelling. Biopsy from swelling revealed as small cell variant of anaplastic lymphoma kinase-positive ALCL. Staging with positron emission tomography–computed tomography showed lymph nodal and multiple extra-nodal involvement. The extra-nodal sites were lung, pancreas, bone, sphenoid sinus and muscles. He was started on ALCL-99 protocol. |
| first_indexed | 2024-04-12T07:01:41Z |
| format | Article |
| id | doaj.art-386b831968f14800b0955f09e951a5a9 |
| institution | Directory Open Access Journal |
| issn | 2277-5706 2277-8357 |
| language | English |
| last_indexed | 2024-04-12T07:01:41Z |
| publishDate | 2019-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Clinical and Scientific Research |
| spelling | doaj.art-386b831968f14800b0955f09e951a5a92022-12-22T03:43:00ZengWolters Kluwer Medknow PublicationsJournal of Clinical and Scientific Research2277-57062277-83572019-01-0182959710.4103/JCSR.JCSR_20_18A rare case of paediatric non-Hodgkin's lymphomaD BhargaviT KannanK L PriyadarshiniV SanthoshK M RamprahladB SreekanthAnaplastic large cell lymphoma (ALCL) is a rare disease accounting for 10%–15% of all non-Hodgkin's lymphomas in children. It is distinguished from other lymphomas by their anaplastic cytology and constant membrane expression of the CD30 antigen. We report a 9-year-old boy presented with a left calf swelling. Biopsy from swelling revealed as small cell variant of anaplastic lymphoma kinase-positive ALCL. Staging with positron emission tomography–computed tomography showed lymph nodal and multiple extra-nodal involvement. The extra-nodal sites were lung, pancreas, bone, sphenoid sinus and muscles. He was started on ALCL-99 protocol.http://www.jcsr.co.in/article.asp?issn=2277-5706;year=2019;volume=8;issue=2;spage=95;epage=97;aulast=Bhargavianaplastic large cell lymphomaanaplastic large cell lymphoma-99anaplastic lymphoma kinase positiveextra-nodalsmall cell variant |
| spellingShingle | D Bhargavi T Kannan K L Priyadarshini V Santhosh K M Ramprahlad B Sreekanth A rare case of paediatric non-Hodgkin's lymphoma Journal of Clinical and Scientific Research anaplastic large cell lymphoma anaplastic large cell lymphoma-99 anaplastic lymphoma kinase positive extra-nodal small cell variant |
| title | A rare case of paediatric non-Hodgkin's lymphoma |
| title_full | A rare case of paediatric non-Hodgkin's lymphoma |
| title_fullStr | A rare case of paediatric non-Hodgkin's lymphoma |
| title_full_unstemmed | A rare case of paediatric non-Hodgkin's lymphoma |
| title_short | A rare case of paediatric non-Hodgkin's lymphoma |
| title_sort | rare case of paediatric non hodgkin s lymphoma |
| topic | anaplastic large cell lymphoma anaplastic large cell lymphoma-99 anaplastic lymphoma kinase positive extra-nodal small cell variant |
| url | http://www.jcsr.co.in/article.asp?issn=2277-5706;year=2019;volume=8;issue=2;spage=95;epage=97;aulast=Bhargavi |
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