Acute myocarditis and acute myopathy as the first manifestations of COVID-19; a case report
Coronavirus disease 2019 (COVID-19) mainly manifests with flu-like and respiratory symptoms such as fever, chill, myalgia, cough, dyspnea and in severe cases, it leads to acute respiratory distress syndrome and respiratory failure. However, there is evidence of extra-pulmonary involvements in patien...
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| Format: | Article |
| Language: | English |
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Society of Diabetic Nephropathy Prevention
2023-01-01
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| Series: | Journal of Nephropharmacology |
| Subjects: | |
| Online Access: | https://jnephropharmacology.com/PDF/npj-12-e10479.pdf |
| _version_ | 1811315090737070080 |
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| author | Fatemeh Yaghoubi Farnaz Tavakoli Fatemeh Ghanbari Nasser Aghdami Davood Babakhani |
| author_facet | Fatemeh Yaghoubi Farnaz Tavakoli Fatemeh Ghanbari Nasser Aghdami Davood Babakhani |
| author_sort | Fatemeh Yaghoubi |
| collection | DOAJ |
| description | Coronavirus disease 2019 (COVID-19) mainly manifests with flu-like and respiratory symptoms such as fever, chill, myalgia, cough, dyspnea and in severe cases, it leads to acute respiratory distress syndrome and respiratory failure. However, there is evidence of extra-pulmonary involvements in patients with COVID-19. Some case reports and studies have reported severe and life-threatening complications related to COVID-19 such as cardiovascular complications (acute heart failure, myocarditis, acute coronary syndrome, thromboembolic events) and neuromuscular complications (stroke, transient ischemic attack, myositis, myopathy, Guillain-Barre syndrome). Here, we report a 51-year-old woman without a previous history of cardiovascular disease or neuromuscular disease referred to the emergency department of our hospital with new onset severe respiratory distress and progressive symmetric quadriparesis. We concluded that, the patient was infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and we therefore have encountered acute myocarditis and acute myopathy due to COVID-19 disease. In the intensive care unit (ICU), the patient was treated with oxygen therapy without mechanical ventilation, dexamethasone, intravenous human immunoglobulin (IVIG), beta interferon and remdesivir. The clinical feature, cardiac, respiratory, neuromuscular and hemodynamic parameters improved clearly five days after taking above mentioned treatments. The troponin, N-terminal pro-B type natriuretic peptide (NT-proBNP), creatine phosphokinase (CPK), returned to normal values. Following improvement of cardiac and neurologic problems, the patient was transferred from ICU to general ward and then after 10 days, she was discharged with oral anticoagulant, anti-platelet, low-dose of corticosteroids and other conservative treatments. |
| first_indexed | 2024-04-13T11:24:04Z |
| format | Article |
| id | doaj.art-3872448f5ac849c890bdb8d9e78b0834 |
| institution | Directory Open Access Journal |
| issn | 2345-4202 |
| language | English |
| last_indexed | 2024-04-13T11:24:04Z |
| publishDate | 2023-01-01 |
| publisher | Society of Diabetic Nephropathy Prevention |
| record_format | Article |
| series | Journal of Nephropharmacology |
| spelling | doaj.art-3872448f5ac849c890bdb8d9e78b08342022-12-22T02:48:45ZengSociety of Diabetic Nephropathy PreventionJournal of Nephropharmacology2345-42022023-01-01121e10479e1047910.34172/npj.2022.10479npj-10479Acute myocarditis and acute myopathy as the first manifestations of COVID-19; a case reportFatemeh Yaghoubi0Farnaz Tavakoli1Fatemeh Ghanbari2Nasser Aghdami3Davood Babakhani4Department of Nephrology and Kidney Transplantation, Dr. Shariati Hospital, Tehran University of Medical Sciences, Tehran, IranDepartment of Nephrology and Kidney Transplantation, Dr. Shariati Hospital, Tehran University of Medical Sciences, Tehran, IranDepartment of Internal Medicine Diseases, Dr. Shariati Hospital, Tehran University of Medical Sciences, Tehran, IranDepartment of Infectious Diseases and Tropical Medicine, Tehran University of Medical Sciences, Tehran, IranHematology, Oncology Research Center and Stem Cell Transplantation (HORCST), Dr. Shariati Hospital, Tehran University of Medical Sciences, Tehran, IranCoronavirus disease 2019 (COVID-19) mainly manifests with flu-like and respiratory symptoms such as fever, chill, myalgia, cough, dyspnea and in severe cases, it leads to acute respiratory distress syndrome and respiratory failure. However, there is evidence of extra-pulmonary involvements in patients with COVID-19. Some case reports and studies have reported severe and life-threatening complications related to COVID-19 such as cardiovascular complications (acute heart failure, myocarditis, acute coronary syndrome, thromboembolic events) and neuromuscular complications (stroke, transient ischemic attack, myositis, myopathy, Guillain-Barre syndrome). Here, we report a 51-year-old woman without a previous history of cardiovascular disease or neuromuscular disease referred to the emergency department of our hospital with new onset severe respiratory distress and progressive symmetric quadriparesis. We concluded that, the patient was infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and we therefore have encountered acute myocarditis and acute myopathy due to COVID-19 disease. In the intensive care unit (ICU), the patient was treated with oxygen therapy without mechanical ventilation, dexamethasone, intravenous human immunoglobulin (IVIG), beta interferon and remdesivir. The clinical feature, cardiac, respiratory, neuromuscular and hemodynamic parameters improved clearly five days after taking above mentioned treatments. The troponin, N-terminal pro-B type natriuretic peptide (NT-proBNP), creatine phosphokinase (CPK), returned to normal values. Following improvement of cardiac and neurologic problems, the patient was transferred from ICU to general ward and then after 10 days, she was discharged with oral anticoagulant, anti-platelet, low-dose of corticosteroids and other conservative treatments.https://jnephropharmacology.com/PDF/npj-12-e10479.pdfcovid-19 diseaseacute myocarditisacute myopathy |
| spellingShingle | Fatemeh Yaghoubi Farnaz Tavakoli Fatemeh Ghanbari Nasser Aghdami Davood Babakhani Acute myocarditis and acute myopathy as the first manifestations of COVID-19; a case report Journal of Nephropharmacology covid-19 disease acute myocarditis acute myopathy |
| title | Acute myocarditis and acute myopathy as the first manifestations of COVID-19; a case report |
| title_full | Acute myocarditis and acute myopathy as the first manifestations of COVID-19; a case report |
| title_fullStr | Acute myocarditis and acute myopathy as the first manifestations of COVID-19; a case report |
| title_full_unstemmed | Acute myocarditis and acute myopathy as the first manifestations of COVID-19; a case report |
| title_short | Acute myocarditis and acute myopathy as the first manifestations of COVID-19; a case report |
| title_sort | acute myocarditis and acute myopathy as the first manifestations of covid 19 a case report |
| topic | covid-19 disease acute myocarditis acute myopathy |
| url | https://jnephropharmacology.com/PDF/npj-12-e10479.pdf |
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