Identification and characterization of Aβ peptide interactors in Alzheimer’s disease by structural approaches

Identification and characterization of Aβ peptide interactors in Alzheimer’s disease by structural approaches

Currently, there are very limited pharmaceutical interventions for Alzheimer’s disease (AD) to alleviate the amyloid burden implicated in the pathophysiology of the disease. AD is characterized immunohistologically by the accumulation of senile plaques in the brain with afflicted patients progressi...

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Bibliographic Details
Main Authors: Keith D Philibert, Robert A Marr, Eric M Norstrom, Marc J Glucksman
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-10-01
Series:Frontiers in Aging Neuroscience
Subjects:
Proteomics
Alzheimer’s disease
EP24.15
transthyretin
Aβ peptide
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2014.00265/full

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