Balloon kyphoplasty or percutaneous vertebroplasty for osteoporotic vertebral compression fracture? An updated systematic review and meta-analysis
BACKGROUND: Both kyphoplasty (KP) and vertebroplasty (VP) are effective for patients with osteoporotic vertebral compression fracture (OVCF), but which approach might be more effective remains unclear, so we decided to update earlier systematic reviews. OBJECTIVE: Review and analyze studies publishe...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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King Faisal Specialist Hospital and Research Centre
2016-05-01
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| Series: | Annals of Saudi Medicine |
| Online Access: | https://www.annsaudimed.net/doi/full/10.5144/0256-4947.2016.165 |
| _version_ | 1818886255614623744 |
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| author | Lin Liang Xinlei Chen Weimin Jiang Xuefeng Li Jie Chen Lijun Wu Yangyi Zhu |
| author_facet | Lin Liang Xinlei Chen Weimin Jiang Xuefeng Li Jie Chen Lijun Wu Yangyi Zhu |
| author_sort | Lin Liang |
| collection | DOAJ |
| description | BACKGROUND: Both kyphoplasty (KP) and vertebroplasty (VP) are effective for patients with osteoporotic vertebral compression fracture (OVCF), but which approach might be more effective remains unclear, so we decided to update earlier systematic reviews. OBJECTIVE: Review and analyze studies published as of August 2015 that compared clinical outcomes and complications of KP versus VP. DESIGN: Systematic review and meta-analysis. SEARCH METHOD: Published reports up to August 2015 were found in PubMed, EMBASE and the Cochrane Central Register of Controlled Trials (CENTRAL). SELECTION CRITERIA: Randomized controlled trials (RCTs) and prospective and retrospective cohort studies comparing KP and VP in patients with OVCF. DATA COLLECTION AND ANALYSIS: Two authors independently assessed the studies and extracted data. RESULTS: Thirty-two studies involving 3274 patients fulfilled the inclusion criteria. There were significant differences between the two groups in short- and long-term postoperative changes in measures of pain intensity and dysfunction (P<.01), in anterior and middle height (P<.01), kyphotic angle (P<.01), and time to injury, but not in posterior height (P=.178). There were no significant differences in the rate of postoperative fractures including adjacent and total fractures, but cement leakage to the intraspinal space was greater in the VP group (P=.035). KP surgery took longer and required a greater volume of injected cement. CONCLUSIONS: KR resulted in better pain relief, improvements in Oswestry dysfunction and radiographic outcomes with less cement leakage, but further RCTs are needed to verify this conclusion. LIMITATIONS: Only four RCTs with a certain of risk of bias. Most studies were observational. |
| first_indexed | 2024-12-19T16:18:26Z |
| format | Article |
| id | doaj.art-3876f68687674d24bdf0b2d30e629ae3 |
| institution | Directory Open Access Journal |
| issn | 0256-4947 0975-4466 |
| language | English |
| last_indexed | 2024-12-19T16:18:26Z |
| publishDate | 2016-05-01 |
| publisher | King Faisal Specialist Hospital and Research Centre |
| record_format | Article |
| series | Annals of Saudi Medicine |
| spelling | doaj.art-3876f68687674d24bdf0b2d30e629ae32022-12-21T20:14:33ZengKing Faisal Specialist Hospital and Research CentreAnnals of Saudi Medicine0256-49470975-44662016-05-0136316517410.5144/0256-4947.2016.165asm-3-165Balloon kyphoplasty or percutaneous vertebroplasty for osteoporotic vertebral compression fracture? An updated systematic review and meta-analysisLin Liang0Xinlei Chen1Weimin Jiang2Xuefeng Li3Jie Chen4Lijun Wu5Yangyi Zhu6From the Department of Orthopaedics, Shangyu People's Hospital, Shaoxing, ChinaFrom the Department of Orthopaedics, The Affiliated Hospital of Nantong University, Nantong, ChinaFrom the Department of Orthopaedics, The First Affiliated Hospital of Soochow University, Suzhou, ChinaFrom the Department of Orthopaedics, The First Affiliated Hospital of Soochow University, Suzhou, ChinaFrom the Department of Orthopaedics, The First Affiliated Hospital of Soochow University, Suzhou, ChinaFrom the Department of Orthopaedics, Shangyu People's Hospital, Shaoxing, ChinaFrom the Department of Orthopaedics, Shangyu People's Hospital, Shaoxing, ChinaBACKGROUND: Both kyphoplasty (KP) and vertebroplasty (VP) are effective for patients with osteoporotic vertebral compression fracture (OVCF), but which approach might be more effective remains unclear, so we decided to update earlier systematic reviews. OBJECTIVE: Review and analyze studies published as of August 2015 that compared clinical outcomes and complications of KP versus VP. DESIGN: Systematic review and meta-analysis. SEARCH METHOD: Published reports up to August 2015 were found in PubMed, EMBASE and the Cochrane Central Register of Controlled Trials (CENTRAL). SELECTION CRITERIA: Randomized controlled trials (RCTs) and prospective and retrospective cohort studies comparing KP and VP in patients with OVCF. DATA COLLECTION AND ANALYSIS: Two authors independently assessed the studies and extracted data. RESULTS: Thirty-two studies involving 3274 patients fulfilled the inclusion criteria. There were significant differences between the two groups in short- and long-term postoperative changes in measures of pain intensity and dysfunction (P<.01), in anterior and middle height (P<.01), kyphotic angle (P<.01), and time to injury, but not in posterior height (P=.178). There were no significant differences in the rate of postoperative fractures including adjacent and total fractures, but cement leakage to the intraspinal space was greater in the VP group (P=.035). KP surgery took longer and required a greater volume of injected cement. CONCLUSIONS: KR resulted in better pain relief, improvements in Oswestry dysfunction and radiographic outcomes with less cement leakage, but further RCTs are needed to verify this conclusion. LIMITATIONS: Only four RCTs with a certain of risk of bias. Most studies were observational.https://www.annsaudimed.net/doi/full/10.5144/0256-4947.2016.165 |
| spellingShingle | Lin Liang Xinlei Chen Weimin Jiang Xuefeng Li Jie Chen Lijun Wu Yangyi Zhu Balloon kyphoplasty or percutaneous vertebroplasty for osteoporotic vertebral compression fracture? An updated systematic review and meta-analysis Annals of Saudi Medicine |
| title | Balloon kyphoplasty or percutaneous vertebroplasty for osteoporotic vertebral compression fracture? An updated systematic review and meta-analysis |
| title_full | Balloon kyphoplasty or percutaneous vertebroplasty for osteoporotic vertebral compression fracture? An updated systematic review and meta-analysis |
| title_fullStr | Balloon kyphoplasty or percutaneous vertebroplasty for osteoporotic vertebral compression fracture? An updated systematic review and meta-analysis |
| title_full_unstemmed | Balloon kyphoplasty or percutaneous vertebroplasty for osteoporotic vertebral compression fracture? An updated systematic review and meta-analysis |
| title_short | Balloon kyphoplasty or percutaneous vertebroplasty for osteoporotic vertebral compression fracture? An updated systematic review and meta-analysis |
| title_sort | balloon kyphoplasty or percutaneous vertebroplasty for osteoporotic vertebral compression fracture an updated systematic review and meta analysis |
| url | https://www.annsaudimed.net/doi/full/10.5144/0256-4947.2016.165 |
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