Experiment on inducing apoptosis of melanoma cells by micro-plasma jet
As a promising cancer treatment method, cold atmospheric plasma has received widespread attention in recent years. However, previous research has focused more on how to realize and expand the anti-cancer scope of plasma jet. There are also studies on the killing of small-scale cancer cells, but the...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
AIP Publishing LLC
2024-03-01
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| Series: | Nanotechnology and Precision Engineering |
| Online Access: | http://dx.doi.org/10.1063/10.0022239 |
| _version_ | 1797278344371240960 |
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| author | Hua Li Qihao Shi Yanhua Yang Jinghao Qi Yuhan Zhang Fengyun Wang Xiaoxia Du Wenxiang Xiao |
| author_facet | Hua Li Qihao Shi Yanhua Yang Jinghao Qi Yuhan Zhang Fengyun Wang Xiaoxia Du Wenxiang Xiao |
| author_sort | Hua Li |
| collection | DOAJ |
| description | As a promising cancer treatment method, cold atmospheric plasma has received widespread attention in recent years. However, previous research has focused more on how to realize and expand the anti-cancer scope of plasma jet. There are also studies on the killing of small-scale cancer cells, but the effects of plasma jet on normal cells and normal cell clusters have been ignored. Therefore, we proposed a 50 µm sized micro-plasma jet device, and used the device to treat melanoma cells (A-375) and human glial cells (HA1800) to evaluate their anti-cancer effects and effects on normal cells. The experimental results show that this kind of micro-plasma jet device can effectively inactivate cancer cells in a short period of time, while having little effect on normal cells. This work provides a certain experimental basis for the application of fine plasma jet to clinically inactivate cancer cells. |
| first_indexed | 2024-03-07T16:00:50Z |
| format | Article |
| id | doaj.art-387b7a602c294da997892c0a0dcd3120 |
| institution | Directory Open Access Journal |
| issn | 2589-5540 |
| language | English |
| last_indexed | 2024-03-07T16:00:50Z |
| publishDate | 2024-03-01 |
| publisher | AIP Publishing LLC |
| record_format | Article |
| series | Nanotechnology and Precision Engineering |
| spelling | doaj.art-387b7a602c294da997892c0a0dcd31202024-03-04T20:16:42ZengAIP Publishing LLCNanotechnology and Precision Engineering2589-55402024-03-0171013002013002-810.1063/10.0022239Experiment on inducing apoptosis of melanoma cells by micro-plasma jetHua Li0Qihao Shi1Yanhua Yang2Jinghao Qi3Yuhan Zhang4Fengyun Wang5Xiaoxia Du6Wenxiang Xiao7School of Life and Environmental Sciences, GuiLin University of Electronic Technology, Guilin, GuangXi 541004, People’s Republic of ChinaSchool of Life and Environmental Sciences, GuiLin University of Electronic Technology, Guilin, GuangXi 541004, People’s Republic of ChinaGuilin URIT MEDICAL Electronic Sales Co., Ltd., Guilin, GuangXi 541004, People’s Republic of ChinaSchool of Life and Environmental Sciences, GuiLin University of Electronic Technology, Guilin, GuangXi 541004, People’s Republic of ChinaSchool of Life and Environmental Sciences, GuiLin University of Electronic Technology, Guilin, GuangXi 541004, People’s Republic of ChinaSchool of Life and Environmental Sciences, GuiLin University of Electronic Technology, Guilin, GuangXi 541004, People’s Republic of ChinaSchool of Life and Environmental Sciences, GuiLin University of Electronic Technology, Guilin, GuangXi 541004, People’s Republic of ChinaSchool of Life and Environmental Sciences, GuiLin University of Electronic Technology, Guilin, GuangXi 541004, People’s Republic of ChinaAs a promising cancer treatment method, cold atmospheric plasma has received widespread attention in recent years. However, previous research has focused more on how to realize and expand the anti-cancer scope of plasma jet. There are also studies on the killing of small-scale cancer cells, but the effects of plasma jet on normal cells and normal cell clusters have been ignored. Therefore, we proposed a 50 µm sized micro-plasma jet device, and used the device to treat melanoma cells (A-375) and human glial cells (HA1800) to evaluate their anti-cancer effects and effects on normal cells. The experimental results show that this kind of micro-plasma jet device can effectively inactivate cancer cells in a short period of time, while having little effect on normal cells. This work provides a certain experimental basis for the application of fine plasma jet to clinically inactivate cancer cells.http://dx.doi.org/10.1063/10.0022239 |
| spellingShingle | Hua Li Qihao Shi Yanhua Yang Jinghao Qi Yuhan Zhang Fengyun Wang Xiaoxia Du Wenxiang Xiao Experiment on inducing apoptosis of melanoma cells by micro-plasma jet Nanotechnology and Precision Engineering |
| title | Experiment on inducing apoptosis of melanoma cells by micro-plasma jet |
| title_full | Experiment on inducing apoptosis of melanoma cells by micro-plasma jet |
| title_fullStr | Experiment on inducing apoptosis of melanoma cells by micro-plasma jet |
| title_full_unstemmed | Experiment on inducing apoptosis of melanoma cells by micro-plasma jet |
| title_short | Experiment on inducing apoptosis of melanoma cells by micro-plasma jet |
| title_sort | experiment on inducing apoptosis of melanoma cells by micro plasma jet |
| url | http://dx.doi.org/10.1063/10.0022239 |
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