Creation of a panel of genetic markers for breeding of a large white breed pigs on the reproductive fitness
The article presents studies of the effect of SNP of genes PRLR, LEP, ESR, FSHb, MC4R, LIF, POU1F1, GH on the reproductive performance of large white pigs. The analysis was carried out using linear models of mixed type. For each variant of SNP, a separate model was used; as a fixed factor in model t...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
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Federal Agricultural Research Center of the North-East named N.V. Rudnitsky
2017-12-01
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| Series: | Аграрная наука Евро-Северо-Востока |
| Subjects: | |
| Online Access: | https://www.agronauka-sv.ru/jour/article/view/179 |
| _version_ | 1826553910675898368 |
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| author | A. Yu. Kolosov M. A. Leonova L. V. Getmantseva |
| author_facet | A. Yu. Kolosov M. A. Leonova L. V. Getmantseva |
| author_sort | A. Yu. Kolosov |
| collection | DOAJ |
| description | The article presents studies of the effect of SNP of genes PRLR, LEP, ESR, FSHb, MC4R, LIF, POU1F1, GH on the reproductive performance of large white pigs. The analysis was carried out using linear models of mixed type. For each variant of SNP, a separate model was used; as a fixed factor in model the genotype for the gene in question was. Another fixed factor in all models was the order of number of farrowing. A randomized factor was individual sow genotypes. As a result of the analysis a significant superiority of the LEP/CC genotype over the LEP/TT genotype was established for all indicators of reproductive qualities: by the number of pigs at birth on 1.55 h. (p = 0.02), for a piglets born alive on 1.8 h. (p = 0.009), by litter weight at birth on 1.91 kg (p = 0.05). According to the ESR gene animals with the ESR/BB genotype also outperformed all their analogues with the ESR/AA genotype (by the number of pigs at birth on 1.36 h. (p = 0.14), by piglets born alive on 0.93 h. (p = 0.005), by the litter weight at birth on 2.24 kg (p = 0.15) The LIF gene was used to determine the genotype LIF/BB (the number of piglets at birth + 1.35 h. (p = 0 , 15), piglets born alive + 1.9 h. (p = 0.04), litter weight at birth + 2.24 kg (p = 0.24) relative to the LIF/AA genotype.) The superiority of the PRLR/55 genotype was established for the PRLR gene (number of piglets at birth + 0.42 head (p = 0.4), piglets born alive + 0.57 h. (p = 0.25), litter weight at birth + 1.96 kg (p = 0.01) relative to the PRLR/AB genotype.) For other genes there are no significant differences in the reproductive qualities between the genotypes. Based on the obtained results a panel of genetic markers for evaluating reproductive qualities of large white pigs was developed, which includes the LEP, ESR, LIF, and PRLR genes. |
| first_indexed | 2024-03-07T19:19:50Z |
| format | Article |
| id | doaj.art-387ba255ecd3429ebf2d3a601b889f07 |
| institution | Directory Open Access Journal |
| issn | 2072-9081 2500-1396 |
| language | Russian |
| last_indexed | 2025-03-14T07:32:32Z |
| publishDate | 2017-12-01 |
| publisher | Federal Agricultural Research Center of the North-East named N.V. Rudnitsky |
| record_format | Article |
| series | Аграрная наука Евро-Северо-Востока |
| spelling | doaj.art-387ba255ecd3429ebf2d3a601b889f072025-03-03T09:39:12ZrusFederal Agricultural Research Center of the North-East named N.V. RudnitskyАграрная наука Евро-Северо-Востока2072-90812500-13962017-12-01066468178Creation of a panel of genetic markers for breeding of a large white breed pigs on the reproductive fitnessA. Yu. Kolosov0M. A. Leonova1L. V. Getmantseva2Donskoy state agrarian universityDonskoy state agrarian universityDonskoy state agrarian universityThe article presents studies of the effect of SNP of genes PRLR, LEP, ESR, FSHb, MC4R, LIF, POU1F1, GH on the reproductive performance of large white pigs. The analysis was carried out using linear models of mixed type. For each variant of SNP, a separate model was used; as a fixed factor in model the genotype for the gene in question was. Another fixed factor in all models was the order of number of farrowing. A randomized factor was individual sow genotypes. As a result of the analysis a significant superiority of the LEP/CC genotype over the LEP/TT genotype was established for all indicators of reproductive qualities: by the number of pigs at birth on 1.55 h. (p = 0.02), for a piglets born alive on 1.8 h. (p = 0.009), by litter weight at birth on 1.91 kg (p = 0.05). According to the ESR gene animals with the ESR/BB genotype also outperformed all their analogues with the ESR/AA genotype (by the number of pigs at birth on 1.36 h. (p = 0.14), by piglets born alive on 0.93 h. (p = 0.005), by the litter weight at birth on 2.24 kg (p = 0.15) The LIF gene was used to determine the genotype LIF/BB (the number of piglets at birth + 1.35 h. (p = 0 , 15), piglets born alive + 1.9 h. (p = 0.04), litter weight at birth + 2.24 kg (p = 0.24) relative to the LIF/AA genotype.) The superiority of the PRLR/55 genotype was established for the PRLR gene (number of piglets at birth + 0.42 head (p = 0.4), piglets born alive + 0.57 h. (p = 0.25), litter weight at birth + 1.96 kg (p = 0.01) relative to the PRLR/AB genotype.) For other genes there are no significant differences in the reproductive qualities between the genotypes. Based on the obtained results a panel of genetic markers for evaluating reproductive qualities of large white pigs was developed, which includes the LEP, ESR, LIF, and PRLR genes.https://www.agronauka-sv.ru/jour/article/view/179snp панельprlrlepesrfshbmc4rlifpou1f1ghsnp panelpigsmarkersprlrlepesrfshbmc4rlifpou1f1ghlinear models |
| spellingShingle | A. Yu. Kolosov M. A. Leonova L. V. Getmantseva Creation of a panel of genetic markers for breeding of a large white breed pigs on the reproductive fitness Аграрная наука Евро-Северо-Востока snp панель prlr lep esr fshb mc4r lif pou1f1 gh snp panel pigs markers prlr lep esr fshb mc4r lif pou1f1 gh linear models |
| title | Creation of a panel of genetic markers for breeding of a large white breed pigs on the reproductive fitness |
| title_full | Creation of a panel of genetic markers for breeding of a large white breed pigs on the reproductive fitness |
| title_fullStr | Creation of a panel of genetic markers for breeding of a large white breed pigs on the reproductive fitness |
| title_full_unstemmed | Creation of a panel of genetic markers for breeding of a large white breed pigs on the reproductive fitness |
| title_short | Creation of a panel of genetic markers for breeding of a large white breed pigs on the reproductive fitness |
| title_sort | creation of a panel of genetic markers for breeding of a large white breed pigs on the reproductive fitness |
| topic | snp панель prlr lep esr fshb mc4r lif pou1f1 gh snp panel pigs markers prlr lep esr fshb mc4r lif pou1f1 gh linear models |
| url | https://www.agronauka-sv.ru/jour/article/view/179 |
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