Genome-wide surveys reveal polarity and cytoskeletal regulators mediate LKB1-associated germline stem cell quiescence

Genome-wide surveys reveal polarity and cytoskeletal regulators mediate LKB1-associated germline stem cell quiescence

Abstract Background Caenorhabditis elegans can endure long periods of environmental stress by altering their development to execute a quiescent state called “dauer”. Previous work has implicated LKB1 - the causative gene in the autosomal dominant, cancer pre-disposing disease called Peutz-Jeghers Sy...

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Bibliographic Details
Main Authors: Pratik Kadekar, Rita Chaouni, Emily Clark, Anna Kazanets, Richard Roy
Format: Article
Language:English
Published: BMC 2018-06-01
Series:BMC Genomics
Subjects:
PAR-4
AMPK
Actin cytoskeleton
Peutz-Jeghers Syndrome
Dauer
Germ line
Online Access:http://link.springer.com/article/10.1186/s12864-018-4847-y

Internet

http://link.springer.com/article/10.1186/s12864-018-4847-y

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