Invasive Bacterial Infections of the Musculoskeletal and Central Nervous System during Pig Rearing: Detection Frequencies of Different Pathogens and Specific <i>Streptococcus suis</i> Genotypes
Locomotor and central nervous system disorders occur during pig rearing, but there is no systematic recording of the different causative agents in Germany. Joint and meningeal swabs, kidneys, lungs, and eight different lymph nodes per pig were cultured, and isolated pathogens were identified using p...
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| Format: | Article |
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MDPI AG
2024-01-01
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| Series: | Veterinary Sciences |
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| Online Access: | https://www.mdpi.com/2306-7381/11/1/17 |
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| author | Ninette Natascha Bornemann Leonie Mayer Sonia Lacouture Marcelo Gottschalk Christoph Georg Baums Katrin Strutzberg-Minder |
| author_facet | Ninette Natascha Bornemann Leonie Mayer Sonia Lacouture Marcelo Gottschalk Christoph Georg Baums Katrin Strutzberg-Minder |
| author_sort | Ninette Natascha Bornemann |
| collection | DOAJ |
| description | Locomotor and central nervous system disorders occur during pig rearing, but there is no systematic recording of the different causative agents in Germany. Joint and meningeal swabs, kidneys, lungs, and eight different lymph nodes per pig were cultured, and isolated pathogens were identified using polymerase chain reactions (PCRs). The <i>cps</i> and pathotype of <i>Streptococcus suis</i> (<i>S. suis</i>) isolates were determined using multiplex-PCR. <i>S. suis</i> was the most important pathogen in the infected joints (70.8%) and meningeal swabs (85.4%) and was most frequently detected in both sites in suckling and weaning piglets. To elucidate the possible portal of entry of <i>S. suis</i>, eight different lymph nodes from 201 pigs were examined in a prospective study. <i>S. suis</i> was detected in all examined lymph nodes (<i>n</i> = 1569), including the mesenteric lymph nodes (15.8%; <i>n</i> = 121/765), with <i>cps</i> 9 (37.2%; <i>n</i> = 147) and <i>cps</i> 2 (24.3%; <i>n</i> = 96) being the most dominating <i>cps</i> types. In piglets with a systemic <i>S. suis</i> infection, different lymph nodes are frequently infected with the invasive <i>S. suis</i> strain, which does not help clarify the portal of entry for <i>S. suis</i>. |
| first_indexed | 2024-03-08T10:33:15Z |
| format | Article |
| id | doaj.art-387fc8f8cebd4fff9d68e16000017cff |
| institution | Directory Open Access Journal |
| issn | 2306-7381 |
| language | English |
| last_indexed | 2024-03-08T10:33:15Z |
| publishDate | 2024-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Veterinary Sciences |
| spelling | doaj.art-387fc8f8cebd4fff9d68e16000017cff2024-01-26T18:45:21ZengMDPI AGVeterinary Sciences2306-73812024-01-011111710.3390/vetsci11010017Invasive Bacterial Infections of the Musculoskeletal and Central Nervous System during Pig Rearing: Detection Frequencies of Different Pathogens and Specific <i>Streptococcus suis</i> GenotypesNinette Natascha Bornemann0Leonie Mayer1Sonia Lacouture2Marcelo Gottschalk3Christoph Georg Baums4Katrin Strutzberg-Minder5IVD Innovative Veterinary Diagnostics (IVD GmbH), Albert-Einstein-Str. 5, 30926 Seelze, GermanyInstitute of Bacteriology and Mycology, Centre for Infectious Diseases, Faculty of Veterinary Medicine, University of Leipzig, 04103 Leipzig, GermanyFaculty of Veterinary Medicine, University of Montreal, Saint-Hyacinthe, QC J2S 2M2, CanadaFaculty of Veterinary Medicine, University of Montreal, Saint-Hyacinthe, QC J2S 2M2, CanadaInstitute of Bacteriology and Mycology, Centre for Infectious Diseases, Faculty of Veterinary Medicine, University of Leipzig, 04103 Leipzig, GermanyIVD Innovative Veterinary Diagnostics (IVD GmbH), Albert-Einstein-Str. 5, 30926 Seelze, GermanyLocomotor and central nervous system disorders occur during pig rearing, but there is no systematic recording of the different causative agents in Germany. Joint and meningeal swabs, kidneys, lungs, and eight different lymph nodes per pig were cultured, and isolated pathogens were identified using polymerase chain reactions (PCRs). The <i>cps</i> and pathotype of <i>Streptococcus suis</i> (<i>S. suis</i>) isolates were determined using multiplex-PCR. <i>S. suis</i> was the most important pathogen in the infected joints (70.8%) and meningeal swabs (85.4%) and was most frequently detected in both sites in suckling and weaning piglets. To elucidate the possible portal of entry of <i>S. suis</i>, eight different lymph nodes from 201 pigs were examined in a prospective study. <i>S. suis</i> was detected in all examined lymph nodes (<i>n</i> = 1569), including the mesenteric lymph nodes (15.8%; <i>n</i> = 121/765), with <i>cps</i> 9 (37.2%; <i>n</i> = 147) and <i>cps</i> 2 (24.3%; <i>n</i> = 96) being the most dominating <i>cps</i> types. In piglets with a systemic <i>S. suis</i> infection, different lymph nodes are frequently infected with the invasive <i>S. suis</i> strain, which does not help clarify the portal of entry for <i>S. suis</i>.https://www.mdpi.com/2306-7381/11/1/17arthritismeningitis<i>Streptococcus suis</i>type of capsulelymph node |
| spellingShingle | Ninette Natascha Bornemann Leonie Mayer Sonia Lacouture Marcelo Gottschalk Christoph Georg Baums Katrin Strutzberg-Minder Invasive Bacterial Infections of the Musculoskeletal and Central Nervous System during Pig Rearing: Detection Frequencies of Different Pathogens and Specific <i>Streptococcus suis</i> Genotypes Veterinary Sciences arthritis meningitis <i>Streptococcus suis</i> type of capsule lymph node |
| title | Invasive Bacterial Infections of the Musculoskeletal and Central Nervous System during Pig Rearing: Detection Frequencies of Different Pathogens and Specific <i>Streptococcus suis</i> Genotypes |
| title_full | Invasive Bacterial Infections of the Musculoskeletal and Central Nervous System during Pig Rearing: Detection Frequencies of Different Pathogens and Specific <i>Streptococcus suis</i> Genotypes |
| title_fullStr | Invasive Bacterial Infections of the Musculoskeletal and Central Nervous System during Pig Rearing: Detection Frequencies of Different Pathogens and Specific <i>Streptococcus suis</i> Genotypes |
| title_full_unstemmed | Invasive Bacterial Infections of the Musculoskeletal and Central Nervous System during Pig Rearing: Detection Frequencies of Different Pathogens and Specific <i>Streptococcus suis</i> Genotypes |
| title_short | Invasive Bacterial Infections of the Musculoskeletal and Central Nervous System during Pig Rearing: Detection Frequencies of Different Pathogens and Specific <i>Streptococcus suis</i> Genotypes |
| title_sort | invasive bacterial infections of the musculoskeletal and central nervous system during pig rearing detection frequencies of different pathogens and specific i streptococcus suis i genotypes |
| topic | arthritis meningitis <i>Streptococcus suis</i> type of capsule lymph node |
| url | https://www.mdpi.com/2306-7381/11/1/17 |
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