Sex-specific effects of aging on humoral immune responses to repeated influenza vaccination in older adults

Sex-specific effects of aging on humoral immune responses to repeated influenza vaccination in older adults

Abstract Older adults (≥65 years of age) bear a significant burden of severe disease and mortality associated with influenza, despite relatively high annual vaccination coverage and substantial pre-existing immunity to influenza. To test the hypothesis that host factors, including age and sex, play...

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Bibliographic Details
Main Authors: Janna R. Shapiro, Huifen Li, Rosemary Morgan, Yiyin Chen, Helen Kuo, Xiaoxuan Ning, Patrick Shea, Cunjin Wu, Katherine Merport, Rayna Saldanha, Suifeng Liu, Engle Abrams, Yan Chen, Denise C. Kelly, Eileen Sheridan-Malone, Lan Wang, Scott L. Zeger, Sabra L. Klein, Sean X. Leng
Format: Article
Language:English
Published: Nature Portfolio 2021-12-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-021-00412-6

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