PERM1 interacts with the MICOS-MIB complex to connect the mitochondria and sarcolemma via ankyrin B
Mitochondria in skeletal muscle have distinct localization and properties through unclear mechanisms. Here, the authors use complexome profiling and immunoprecipitations to identify PERM1 as a MICOS-MIB complex interactor that also binds ankyrin B, suggesting PERM1 directs the mitochondria to the me...
Full description
Bibliographic Details
Main Authors: |
Theresa Bock,
Clara Türk,
Sriram Aravamudhan,
Lena Keufgens,
Wilhelm Bloch,
Dieu Hien Rozsivalova,
Vanina Romanello,
Leonardo Nogara,
Bert Blaauw,
Aleksandra Trifunovic,
Thomas Braun,
Marcus Krüger |
Format: | Article
|
Language: | English |
Published: |
Nature Portfolio
2021-08-01
|
Series: | Nature Communications
|
Online Access: | https://doi.org/10.1038/s41467-021-25185-3
|