Primary urachal signet ring cell carcinoma: A case report

Urachal signet ring cell carcinoma is a kind of rare but aggressive tumor, and a few cases have been reported previously. A 49-year-old male patient with primary complaints of increased frequency of urination, urodynia, and hematuria was diagnosed to have primary urachal signet ring cell carcinoma b...

Full description

Bibliographic Details
Main Authors: Qing Wang, Xiaolong Chen, Jianqing Zhang, Yuting Luo, Kehua Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.1034245/full
_version_ 1811229221734842368
author Qing Wang
Xiaolong Chen
Jianqing Zhang
Yuting Luo
Kehua Jiang
author_facet Qing Wang
Xiaolong Chen
Jianqing Zhang
Yuting Luo
Kehua Jiang
author_sort Qing Wang
collection DOAJ
description Urachal signet ring cell carcinoma is a kind of rare but aggressive tumor, and a few cases have been reported previously. A 49-year-old male patient with primary complaints of increased frequency of urination, urodynia, and hematuria was diagnosed to have primary urachal signet ring cell carcinoma by our department. Multiple metastases were found in the sigmoid colon, terminal ileum, mesentery, and peritoneum during the operation, and palliative surgery involving partial cystectomy with en bloc resection of the urachus was then performed. A chemotherapy regimen of fluorouracil combined with cisplatin was made for this case. In addition, this patient also received anlotinib for targeted therapy. So far, this patient has done well on regular follow-up for 6 months and is in stable condition. We reported this additional urachal signet ring cell carcinoma case and conducted a literature review to strengthen our cognition of this disease.
first_indexed 2024-04-12T10:10:48Z
format Article
id doaj.art-388ad8229e9345d091588ebe2b47d9b1
institution Directory Open Access Journal
issn 2234-943X
language English
last_indexed 2024-04-12T10:10:48Z
publishDate 2022-10-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Oncology
spelling doaj.art-388ad8229e9345d091588ebe2b47d9b12022-12-22T03:37:18ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2022-10-011210.3389/fonc.2022.10342451034245Primary urachal signet ring cell carcinoma: A case reportQing Wang0Xiaolong Chen1Jianqing Zhang2Yuting Luo3Kehua Jiang4Department of Urology, Guizhou Provincial People’s Hospital, Guiyang, ChinaDepartment of Urology, Guizhou Provincial People’s Hospital, Guiyang, ChinaZunyi Medical University, Zunyi, ChinaDepartment of Urology, Guizhou Provincial People’s Hospital, Guiyang, ChinaDepartment of Urology, Guizhou Provincial People’s Hospital, Guiyang, ChinaUrachal signet ring cell carcinoma is a kind of rare but aggressive tumor, and a few cases have been reported previously. A 49-year-old male patient with primary complaints of increased frequency of urination, urodynia, and hematuria was diagnosed to have primary urachal signet ring cell carcinoma by our department. Multiple metastases were found in the sigmoid colon, terminal ileum, mesentery, and peritoneum during the operation, and palliative surgery involving partial cystectomy with en bloc resection of the urachus was then performed. A chemotherapy regimen of fluorouracil combined with cisplatin was made for this case. In addition, this patient also received anlotinib for targeted therapy. So far, this patient has done well on regular follow-up for 6 months and is in stable condition. We reported this additional urachal signet ring cell carcinoma case and conducted a literature review to strengthen our cognition of this disease.https://www.frontiersin.org/articles/10.3389/fonc.2022.1034245/fullcase reportdiagnosissignet ring cell carcinomatreatmenturachal carcinoma
spellingShingle Qing Wang
Xiaolong Chen
Jianqing Zhang
Yuting Luo
Kehua Jiang
Primary urachal signet ring cell carcinoma: A case report
Frontiers in Oncology
case report
diagnosis
signet ring cell carcinoma
treatment
urachal carcinoma
title Primary urachal signet ring cell carcinoma: A case report
title_full Primary urachal signet ring cell carcinoma: A case report
title_fullStr Primary urachal signet ring cell carcinoma: A case report
title_full_unstemmed Primary urachal signet ring cell carcinoma: A case report
title_short Primary urachal signet ring cell carcinoma: A case report
title_sort primary urachal signet ring cell carcinoma a case report
topic case report
diagnosis
signet ring cell carcinoma
treatment
urachal carcinoma
url https://www.frontiersin.org/articles/10.3389/fonc.2022.1034245/full
work_keys_str_mv AT qingwang primaryurachalsignetringcellcarcinomaacasereport
AT xiaolongchen primaryurachalsignetringcellcarcinomaacasereport
AT jianqingzhang primaryurachalsignetringcellcarcinomaacasereport
AT yutingluo primaryurachalsignetringcellcarcinomaacasereport
AT kehuajiang primaryurachalsignetringcellcarcinomaacasereport