Nicolau Syndrome in a Child Caused by Penicillin Injection
A wide range of side effects can occur during drug administration. Nicolau Syndrome (NS) is a rare iatrogenic side effect of medications injected Intramuscularly (i.m.). The clinical manifestations range from localised pain and erythema to total necrosis requiring amputation. The present report is a...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Private Limited
2022-01-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://www.jcdr.net/articles/PDF/15912/51750_CE[Ra1]_F(SL)_PF1(AG_SHU)_PFA(AG_KM)_PN(KM).pdf |
| _version_ | 1797939148448858112 |
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| author | Rafat Abdulroof Alkadi Ahmed Saleh Hudna Mohammed Ali Al-Shehab Omar Alzomor |
| author_facet | Rafat Abdulroof Alkadi Ahmed Saleh Hudna Mohammed Ali Al-Shehab Omar Alzomor |
| author_sort | Rafat Abdulroof Alkadi |
| collection | DOAJ |
| description | A wide range of side effects can occur during drug administration. Nicolau Syndrome (NS) is a rare iatrogenic side effect of medications injected Intramuscularly (i.m.). The clinical manifestations range from localised pain and erythema to total necrosis requiring amputation. The present report is about a five-year-old boy, who developed NS after receiving an i.m. injection of benzathine penicillin for treatment of pharyngitis. He developed symptoms minutes after the injection including intense pain at the site of injection followed by progressive discolouration and impairment of movement of the affected limb. The patient was treated with pentoxifylline, methylprednisolone, heparin and antibiotics in a hospital and after one month, complete improvement was noticed. |
| first_indexed | 2024-04-10T19:11:57Z |
| format | Article |
| id | doaj.art-388c8bfa0d844e04997785f22d4dfce9 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-04-10T19:11:57Z |
| publishDate | 2022-01-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-388c8bfa0d844e04997785f22d4dfce92023-01-30T11:08:45ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2022-01-01161SD01SD0310.7860/JCDR/2022/51750.15912Nicolau Syndrome in a Child Caused by Penicillin InjectionRafat Abdulroof Alkadi0Ahmed Saleh Hudna1Mohammed Ali Al-Shehab2Omar Alzomor3Senior Specialist, Department of Paediatrics, University of Science and Technology Hospital, Sana’a, Yemen.Assistant Professor, Department of Paediatrics, University of Science and Technology, Sana’a, Yemen.Senior Specialist, Department of Paediatrics, University of Science and Technology Hospital, Sana’a, Yemen.Consultant, Department of Paediatric Infectious Diseases, King Saud Medical City, Riyadh, Saudi Arabia.A wide range of side effects can occur during drug administration. Nicolau Syndrome (NS) is a rare iatrogenic side effect of medications injected Intramuscularly (i.m.). The clinical manifestations range from localised pain and erythema to total necrosis requiring amputation. The present report is about a five-year-old boy, who developed NS after receiving an i.m. injection of benzathine penicillin for treatment of pharyngitis. He developed symptoms minutes after the injection including intense pain at the site of injection followed by progressive discolouration and impairment of movement of the affected limb. The patient was treated with pentoxifylline, methylprednisolone, heparin and antibiotics in a hospital and after one month, complete improvement was noticed.https://www.jcdr.net/articles/PDF/15912/51750_CE[Ra1]_F(SL)_PF1(AG_SHU)_PFA(AG_KM)_PN(KM).pdfbenzathineintramuscularlivedo reticularispentoxifylline |
| spellingShingle | Rafat Abdulroof Alkadi Ahmed Saleh Hudna Mohammed Ali Al-Shehab Omar Alzomor Nicolau Syndrome in a Child Caused by Penicillin Injection Journal of Clinical and Diagnostic Research benzathine intramuscular livedo reticularis pentoxifylline |
| title | Nicolau Syndrome in a Child Caused by Penicillin Injection |
| title_full | Nicolau Syndrome in a Child Caused by Penicillin Injection |
| title_fullStr | Nicolau Syndrome in a Child Caused by Penicillin Injection |
| title_full_unstemmed | Nicolau Syndrome in a Child Caused by Penicillin Injection |
| title_short | Nicolau Syndrome in a Child Caused by Penicillin Injection |
| title_sort | nicolau syndrome in a child caused by penicillin injection |
| topic | benzathine intramuscular livedo reticularis pentoxifylline |
| url | https://www.jcdr.net/articles/PDF/15912/51750_CE[Ra1]_F(SL)_PF1(AG_SHU)_PFA(AG_KM)_PN(KM).pdf |
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