Mitochondria-targeted nanoplatforms for enhanced photodynamic therapy against hypoxia tumor

Mitochondria-targeted nanoplatforms for enhanced photodynamic therapy against hypoxia tumor

Abstract Background Photodynamic therapy (PDT) is a promising therapeutic modality that can convert oxygen into cytotoxic reactive oxygen species (ROS) via photosensitizers to halt tumor growth. However, hypoxia and the unsatisfactory accumulation of photosensitizers in tumors severely diminish the...

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Bibliographic Details
Main Authors: Jiexin Wen, Yong Luo, Hui Gao, Liang Zhang, Xiang Wang, Ju Huang, Tingting Shang, Di Zhou, Dong Wang, Zhigang Wang, Pan Li, Zhaoxia Wang
Format: Article
Language:English
Published: BMC 2021-12-01
Series:Journal of Nanobiotechnology
Subjects:
Hypoxic tumor
3-Bromopyruvate
Respiration inhibition
Photodynamic therapy
Nanomedicine
Online Access:https://doi.org/10.1186/s12951-021-01196-6

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