Cytotoxic Natural Products from Marine Sponge-Derived Microorganisms

A growing body of evidence indicates that marine sponge-derived microbes possess the potential ability to make prolific natural products with therapeutic effects. This review for the first time provides a comprehensive overview of new cytotoxic agents from these marine microbes over the last 62 year...

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Main Authors: Huawei Zhang, Ziping Zhao, Hong Wang
Format: Article
Language:English
Published: MDPI AG 2017-03-01
Series:Marine Drugs
Subjects:
Online Access:http://www.mdpi.com/1660-3397/15/3/68
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author Huawei Zhang
Ziping Zhao
Hong Wang
author_facet Huawei Zhang
Ziping Zhao
Hong Wang
author_sort Huawei Zhang
collection DOAJ
description A growing body of evidence indicates that marine sponge-derived microbes possess the potential ability to make prolific natural products with therapeutic effects. This review for the first time provides a comprehensive overview of new cytotoxic agents from these marine microbes over the last 62 years from 1955 to 2016, which are assorted into seven types: terpenes, alkaloids, peptides, aromatics, lactones, steroids, and miscellaneous compounds.
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spelling doaj.art-388d7754d41c46c18115f4f4674875a12022-12-22T04:24:36ZengMDPI AGMarine Drugs1660-33972017-03-011536810.3390/md15030068md15030068Cytotoxic Natural Products from Marine Sponge-Derived MicroorganismsHuawei Zhang0Ziping Zhao1Hong Wang2School of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou 310014, ChinaSchool of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou 310014, ChinaSchool of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou 310014, ChinaA growing body of evidence indicates that marine sponge-derived microbes possess the potential ability to make prolific natural products with therapeutic effects. This review for the first time provides a comprehensive overview of new cytotoxic agents from these marine microbes over the last 62 years from 1955 to 2016, which are assorted into seven types: terpenes, alkaloids, peptides, aromatics, lactones, steroids, and miscellaneous compounds.http://www.mdpi.com/1660-3397/15/3/68marine microbesponge-derived microbenatural productcytotoxic compound
spellingShingle Huawei Zhang
Ziping Zhao
Hong Wang
Cytotoxic Natural Products from Marine Sponge-Derived Microorganisms
Marine Drugs
marine microbe
sponge-derived microbe
natural product
cytotoxic compound
title Cytotoxic Natural Products from Marine Sponge-Derived Microorganisms
title_full Cytotoxic Natural Products from Marine Sponge-Derived Microorganisms
title_fullStr Cytotoxic Natural Products from Marine Sponge-Derived Microorganisms
title_full_unstemmed Cytotoxic Natural Products from Marine Sponge-Derived Microorganisms
title_short Cytotoxic Natural Products from Marine Sponge-Derived Microorganisms
title_sort cytotoxic natural products from marine sponge derived microorganisms
topic marine microbe
sponge-derived microbe
natural product
cytotoxic compound
url http://www.mdpi.com/1660-3397/15/3/68
work_keys_str_mv AT huaweizhang cytotoxicnaturalproductsfrommarinespongederivedmicroorganisms
AT zipingzhao cytotoxicnaturalproductsfrommarinespongederivedmicroorganisms
AT hongwang cytotoxicnaturalproductsfrommarinespongederivedmicroorganisms