Phenotype analysis of families with TP53 germline variants at the Center for Familial Breast and Ovarian Cancer, Cologne

Phenotype analysis of families with TP53 germline variants at the Center for Familial Breast and Ovarian Cancer, Cologne

Abstract Purpose Tumor protein p53 (TP53) pathogenic variant (PV) carriers are identified during genetic testing for hereditary causes of cancer. PVs in TP53 are associated with the Li‐Fraumeni syndrome (LFS), and thus, surveillance and preventive measures are important for TP53 PV carriers. However...

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Bibliographic Details
Main Authors:	K. Kast, K. Rhiem, M. Larsen, B. Wappenschmidt, R. Schmutzler
Format:	Article
Language:	English
Published:	Wiley 2024-02-01
Series:	Cancer Medicine
Subjects:	breast cancer cancer prevention genetic variants next‐generation sequencing
Online Access:	https://doi.org/10.1002/cam4.6920

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