Polyacrylamide Hydrogel (Bulkamid) in Female Patients of 80 or More Years with Urinary Incontinence

Introduction: To assess the effectiveness of polyacrylamide hydrogel (Bulkamid ®) in injection therapy for urinary incontinence in women of 80 or more years. Materials and Methods: Twenty consecutive women mean age 84.5 (range 80-87) with stress or mixed urinary incontinence were enrolled in this...

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Main Authors: Carlo Vecchioli-Scaldazza, Carolina Morosetti, Berouz Azizi, Willy Giannubilo, Vincenzo Ferrara
Format: Article
Language:English
Published: Sociedade Brasileira de Urologia 2014-01-01
Series:International Brazilian Journal of Urology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382014000100037&lng=en&tlng=en
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author Carlo Vecchioli-Scaldazza
Carolina Morosetti
Berouz Azizi
Willy Giannubilo
Vincenzo Ferrara
author_facet Carlo Vecchioli-Scaldazza
Carolina Morosetti
Berouz Azizi
Willy Giannubilo
Vincenzo Ferrara
author_sort Carlo Vecchioli-Scaldazza
collection DOAJ
description Introduction: To assess the effectiveness of polyacrylamide hydrogel (Bulkamid ®) in injection therapy for urinary incontinence in women of 80 or more years. Materials and Methods: Twenty consecutive women mean age 84.5 (range 80-87) with stress or mixed urinary incontinence were enrolled in this prospective study. All subjects were evaluated at baseline and re-evaluated 7 days, 6,12,18 and 24 months after treatment. A detailed clinical evaluation, physical examination, daily pad count, urodynamic investigation and evaluation of urethral mobility by trans-labial ultrasound were performed. Results: A statistically significant decrease in the number of pads was observed in the follow-up (p = 0.0002 after 24 months). Physical examination showed a statistically significant lack or reduced lost of urine with stress test (p = 0.0163 after 24 months). Urodynamic findings showed an increase of Valsalva leak point pressure, maximum urethral closure pressure and functional length. Maximum flow and post void residual were respectively observed to be significantly reduced and increased only after 7 days from injection therapy. Quality of life (QoL) assessed with the Incontinence Impact questionnaire short form (IIQ-7) showed a statistically significant improvement (p = 0.0001 after 24 months). Patient satisfaction assessed with the Visual Analogue Scale and Patient Global Impression of Improvement questionnaire respectively produced evaluation of “satisfied” and “much improved” even after 24 months. Conclusions: Polyacrylamide hydrogel (Bulkamid®) is an effective treatment with low morbility in patients of 80 or more years.
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spelling doaj.art-389a6be7d4ad473a8b7bd8703f2f8a792022-12-22T02:13:37ZengSociedade Brasileira de UrologiaInternational Brazilian Journal of Urology1677-61192014-01-01401374310.1590/S1677-5538.IBJU.2014.01.06S1677-55382014000100037Polyacrylamide Hydrogel (Bulkamid) in Female Patients of 80 or More Years with Urinary IncontinenceCarlo Vecchioli-ScaldazzaCarolina MorosettiBerouz AziziWilly GiannubiloVincenzo FerraraIntroduction: To assess the effectiveness of polyacrylamide hydrogel (Bulkamid ®) in injection therapy for urinary incontinence in women of 80 or more years. Materials and Methods: Twenty consecutive women mean age 84.5 (range 80-87) with stress or mixed urinary incontinence were enrolled in this prospective study. All subjects were evaluated at baseline and re-evaluated 7 days, 6,12,18 and 24 months after treatment. A detailed clinical evaluation, physical examination, daily pad count, urodynamic investigation and evaluation of urethral mobility by trans-labial ultrasound were performed. Results: A statistically significant decrease in the number of pads was observed in the follow-up (p = 0.0002 after 24 months). Physical examination showed a statistically significant lack or reduced lost of urine with stress test (p = 0.0163 after 24 months). Urodynamic findings showed an increase of Valsalva leak point pressure, maximum urethral closure pressure and functional length. Maximum flow and post void residual were respectively observed to be significantly reduced and increased only after 7 days from injection therapy. Quality of life (QoL) assessed with the Incontinence Impact questionnaire short form (IIQ-7) showed a statistically significant improvement (p = 0.0001 after 24 months). Patient satisfaction assessed with the Visual Analogue Scale and Patient Global Impression of Improvement questionnaire respectively produced evaluation of “satisfied” and “much improved” even after 24 months. Conclusions: Polyacrylamide hydrogel (Bulkamid®) is an effective treatment with low morbility in patients of 80 or more years.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382014000100037&lng=en&tlng=enInjectionsNeuromuscular Blocking AgentsUrinary IncontinenceFemaleQuality of Life
spellingShingle Carlo Vecchioli-Scaldazza
Carolina Morosetti
Berouz Azizi
Willy Giannubilo
Vincenzo Ferrara
Polyacrylamide Hydrogel (Bulkamid) in Female Patients of 80 or More Years with Urinary Incontinence
International Brazilian Journal of Urology
Injections
Neuromuscular Blocking Agents
Urinary Incontinence
Female
Quality of Life
title Polyacrylamide Hydrogel (Bulkamid) in Female Patients of 80 or More Years with Urinary Incontinence
title_full Polyacrylamide Hydrogel (Bulkamid) in Female Patients of 80 or More Years with Urinary Incontinence
title_fullStr Polyacrylamide Hydrogel (Bulkamid) in Female Patients of 80 or More Years with Urinary Incontinence
title_full_unstemmed Polyacrylamide Hydrogel (Bulkamid) in Female Patients of 80 or More Years with Urinary Incontinence
title_short Polyacrylamide Hydrogel (Bulkamid) in Female Patients of 80 or More Years with Urinary Incontinence
title_sort polyacrylamide hydrogel bulkamid in female patients of 80 or more years with urinary incontinence
topic Injections
Neuromuscular Blocking Agents
Urinary Incontinence
Female
Quality of Life
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382014000100037&lng=en&tlng=en
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