Polyacrylamide Hydrogel (Bulkamid) in Female Patients of 80 or More Years with Urinary Incontinence
Introduction: To assess the effectiveness of polyacrylamide hydrogel (Bulkamid ®) in injection therapy for urinary incontinence in women of 80 or more years. Materials and Methods: Twenty consecutive women mean age 84.5 (range 80-87) with stress or mixed urinary incontinence were enrolled in this...
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Sociedade Brasileira de Urologia
2014-01-01
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Series: | International Brazilian Journal of Urology |
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Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382014000100037&lng=en&tlng=en |
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author | Carlo Vecchioli-Scaldazza Carolina Morosetti Berouz Azizi Willy Giannubilo Vincenzo Ferrara |
author_facet | Carlo Vecchioli-Scaldazza Carolina Morosetti Berouz Azizi Willy Giannubilo Vincenzo Ferrara |
author_sort | Carlo Vecchioli-Scaldazza |
collection | DOAJ |
description | Introduction: To assess the effectiveness of polyacrylamide hydrogel (Bulkamid ®) in injection therapy for urinary incontinence in women of 80 or more years. Materials and Methods: Twenty consecutive women mean age 84.5 (range 80-87) with stress or mixed urinary incontinence were enrolled in this prospective study. All subjects were evaluated at baseline and re-evaluated 7 days, 6,12,18 and 24 months after treatment. A detailed clinical evaluation, physical examination, daily pad count, urodynamic investigation and evaluation of urethral mobility by trans-labial ultrasound were performed. Results: A statistically significant decrease in the number of pads was observed in the follow-up (p = 0.0002 after 24 months). Physical examination showed a statistically significant lack or reduced lost of urine with stress test (p = 0.0163 after 24 months). Urodynamic findings showed an increase of Valsalva leak point pressure, maximum urethral closure pressure and functional length. Maximum flow and post void residual were respectively observed to be significantly reduced and increased only after 7 days from injection therapy. Quality of life (QoL) assessed with the Incontinence Impact questionnaire short form (IIQ-7) showed a statistically significant improvement (p = 0.0001 after 24 months). Patient satisfaction assessed with the Visual Analogue Scale and Patient Global Impression of Improvement questionnaire respectively produced evaluation of “satisfied” and “much improved” even after 24 months. Conclusions: Polyacrylamide hydrogel (Bulkamid®) is an effective treatment with low morbility in patients of 80 or more years. |
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format | Article |
id | doaj.art-389a6be7d4ad473a8b7bd8703f2f8a79 |
institution | Directory Open Access Journal |
issn | 1677-6119 |
language | English |
last_indexed | 2024-04-14T03:58:54Z |
publishDate | 2014-01-01 |
publisher | Sociedade Brasileira de Urologia |
record_format | Article |
series | International Brazilian Journal of Urology |
spelling | doaj.art-389a6be7d4ad473a8b7bd8703f2f8a792022-12-22T02:13:37ZengSociedade Brasileira de UrologiaInternational Brazilian Journal of Urology1677-61192014-01-01401374310.1590/S1677-5538.IBJU.2014.01.06S1677-55382014000100037Polyacrylamide Hydrogel (Bulkamid) in Female Patients of 80 or More Years with Urinary IncontinenceCarlo Vecchioli-ScaldazzaCarolina MorosettiBerouz AziziWilly GiannubiloVincenzo FerraraIntroduction: To assess the effectiveness of polyacrylamide hydrogel (Bulkamid ®) in injection therapy for urinary incontinence in women of 80 or more years. Materials and Methods: Twenty consecutive women mean age 84.5 (range 80-87) with stress or mixed urinary incontinence were enrolled in this prospective study. All subjects were evaluated at baseline and re-evaluated 7 days, 6,12,18 and 24 months after treatment. A detailed clinical evaluation, physical examination, daily pad count, urodynamic investigation and evaluation of urethral mobility by trans-labial ultrasound were performed. Results: A statistically significant decrease in the number of pads was observed in the follow-up (p = 0.0002 after 24 months). Physical examination showed a statistically significant lack or reduced lost of urine with stress test (p = 0.0163 after 24 months). Urodynamic findings showed an increase of Valsalva leak point pressure, maximum urethral closure pressure and functional length. Maximum flow and post void residual were respectively observed to be significantly reduced and increased only after 7 days from injection therapy. Quality of life (QoL) assessed with the Incontinence Impact questionnaire short form (IIQ-7) showed a statistically significant improvement (p = 0.0001 after 24 months). Patient satisfaction assessed with the Visual Analogue Scale and Patient Global Impression of Improvement questionnaire respectively produced evaluation of “satisfied” and “much improved” even after 24 months. Conclusions: Polyacrylamide hydrogel (Bulkamid®) is an effective treatment with low morbility in patients of 80 or more years.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382014000100037&lng=en&tlng=enInjectionsNeuromuscular Blocking AgentsUrinary IncontinenceFemaleQuality of Life |
spellingShingle | Carlo Vecchioli-Scaldazza Carolina Morosetti Berouz Azizi Willy Giannubilo Vincenzo Ferrara Polyacrylamide Hydrogel (Bulkamid) in Female Patients of 80 or More Years with Urinary Incontinence International Brazilian Journal of Urology Injections Neuromuscular Blocking Agents Urinary Incontinence Female Quality of Life |
title | Polyacrylamide Hydrogel (Bulkamid) in Female Patients of 80 or More Years with Urinary Incontinence |
title_full | Polyacrylamide Hydrogel (Bulkamid) in Female Patients of 80 or More Years with Urinary Incontinence |
title_fullStr | Polyacrylamide Hydrogel (Bulkamid) in Female Patients of 80 or More Years with Urinary Incontinence |
title_full_unstemmed | Polyacrylamide Hydrogel (Bulkamid) in Female Patients of 80 or More Years with Urinary Incontinence |
title_short | Polyacrylamide Hydrogel (Bulkamid) in Female Patients of 80 or More Years with Urinary Incontinence |
title_sort | polyacrylamide hydrogel bulkamid in female patients of 80 or more years with urinary incontinence |
topic | Injections Neuromuscular Blocking Agents Urinary Incontinence Female Quality of Life |
url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382014000100037&lng=en&tlng=en |
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